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    Glossary Hereditary Hypotrichosis Simplex

    genetic condition causing progressive hair thinning and loss

    Hereditary Hypotrichosis Simplex (HHS) is a genetic condition characterized by progressive hair thinning and loss, typically beginning in childhood or adolescence. Unlike other forms of hair loss, HHS does not involve scarring or other skin abnormalities, and it primarily affects the scalp, leading to sparse or absent hair over time.

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    Research 10 of 1000+

    1. APCDD1 is a novel Wnt inhibitor mutated in hereditary hypotrichosis simplex Nature · 2010 · 199 citations
    2. A distinct gene close to the hairless locus on chromosome 8p underlies hereditary Marie Unna type hypotrichosis in a German family British Journal of Dermatology · 2000 · 36 citations
    3. A new locus for hereditary hypotrichosis simplex maps to chromosome 13q12.12∼12.3 in a Chinese family Journal of Cutaneous Pathology · 2010 · 7 citations
    4. Hereditary Hypotrichosis and Localized Morphea: A New Clinical Entity Pediatric Dermatology · 1986 · 5 citations
    5. Whole-genome SNP genotyping mapped a novel locus for hereditary hypotrichosis on chromosome 2q31.1–q32.2 Journal of Dermatological Science · 2015
    6. Isotretinoin-induced hair growth in a case of hereditary hypotrichosis simplex of the scalp: A promising therapeutic approach JAAD Case Reports · 2024
    7. Successful treatment of hereditary hypotrichosis simplex by platelet rich plasma injection with topical minoxidil 2% Journal of Dermatological Treatment · 2023
    8. Treatment of hereditary hypotrichosis simplex of the scalp with oral minoxidil and growth factors Dermatologic Therapy · 2022
    9. Marie‐Unna Hereditary Hypotrichosis: Case Report and Review of the Literature Pediatric dermatology · 2011
    10. Marie‐Unna Hereditary Hypotrichosis: Case Report and Review of the Literature Pediatric dermatology · 2011 · 12 citations
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    Community 3 of 10

    1. Hereditary hair loss want your advice Reddit · 25 Sept 2026
    2. 2.5 Months Into Treatment for Hereditary Hair Loss – Before & After Reddit · 10 Jun 2025
    3. Are Fin sides hereditary? And questions on steps to take before starting inc. supplements (22M) Reddit · 13 Dec 2021
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