May 2026 in “Journal of the Egyptian Womenʼs Dermatologic Society” This study found that post-COVID-19 telogen effluvium is strongly associated with elevated oxidative stress marker sRAGE and reduced antioxidant marker HO-1, suggesting potential biomarkers for early diagnosis and monitoring.
1 citations
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March 2024 in “Journal of Cellular and Molecular Medicine” In this study, researchers found that 4-Octyl itaconate (4-OI) inhibited cisplatin-induced ferroptosis and protected auditory cells by activating the NRF2/HO-1 signaling pathway, suggesting a potential therapeutic approach for reducing hearing loss associated with cisplatin treatment.
April 2018 in “Journal of Investigative Dermatology” This study found that Mentha suaveolens aqueous extract activated Nrf-2 and increased detoxifying enzyme expression in keratinocytes, providing protection against oxidative stress without cytotoxicity.
9 citations
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July 2018 in “Current Pharmaceutical Design” This review discusses the importance of heme oxygenase in skin physiology and disease, but it reports no new clinical results; the authors highlight its potential as a treatment target for conditions like atopic dermatitis and psoriasis.
2 citations
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August 2020 in “Journal of Nutritional Science and Vitaminology” In this study, yellow Chinese chive extract was observed to protect against acetaminophen-induced liver toxicity in mice by enhancing antioxidant pathways and reducing liver injury markers.