Search

for
Search:

Did you mean Secondary Intention Healing?

Glossary Secondary Intention Healing

wound heals naturally from the bottom up without stitches

Secondary Intention Healing refers to the process by which a wound heals naturally without surgical closure. Instead of stitching the wound edges together, the wound is left open and heals from the bottom up, through the formation of granulation tissue, contraction, and epithelialization. This method is often used for large, infected, or non-approximable wounds and typically results in a larger scar compared to primary intention healing.

Related Terms

Research

5 / 1000+ results

research Never too old to regenerate? Wound induced hair follicle neogenesis after secondary intention healing in a geriatric patient

7 citations , January 2018 in “Journal of Tissue Viability”

This case report describes an 80-year-old patient whose scalp wound healed by secondary intention, with unexpected hair regrowth observed at 180 days, suggesting hair neogenesis is possible even in older adults.

research Surgical excision of acne keloidalis nuchae with secondary intention healing

24 citations , October 2007 in “Clinical and experimental dermatology”

This case report describes two men with acne keloidalis nuchae who experienced successful outcomes with excision followed by secondary intention healing, resulting in good cosmetic results and minimal recurrence.

research γδ T cells mediate a requisite portion of a wound healing response triggered by cutaneous poxvirus infection

1 citations , September 2020 in “bioRxiv (Cold Spring Harbor Laboratory)”

This study found that skin-resident and recruited γδ T cells play a crucial role in an early wound healing response following cutaneous vaccinia virus infection, rather than in controlling virus replication.

research Beyond Comfortable: A Removable Antibacterial Electroconductive Cellulose Nonwoven Dressing for Accelerated Wound Healing

2 citations , December 2025 in “Nano Letters”

This study developed a tannin-modified cellulose-polypyrrole dressing that accelerates wound healing by enhancing granulation tissue, optimizing collagen, and stimulating angiogenesis, while providing antibacterial protection against S. aureus and E. coli.

Hyaluronic Acid Hydrogel Incorporating Dexpanthenol-Engineered Extracellular Vesicles for Accelerated Wound Closure and Mitigated Secondary Infection Risk

research Hyaluronic Acid Hydrogel Incorporating Dexpanthenol-Engineered Extracellular Vesicles for Accelerated Wound Closure and Mitigated Secondary Infection Risk

August 2026 in “Pharmaceutics”

In this study, researchers developed a dexpanthenol-infused nanotechnological platform within hyaluronic acid hydrogels that promoted wound healing in mice by providing a protective barrier and significantly enhancing skin regeneration, including increased fibroblast activity and tissue remodeling.

View more "healing by secondary intention" in research →

Community Join

5 / 724 results

community Are Derma Rollers Actually Harmful in the Long Run?

in Microneedling 40 upvotes 1 year ago

Derma rollers may cause scarring alopecia, leading some to prefer dermastamps or dermapens for microneedling. Combining minoxidil with microneedling is effective, but proper technique and healing time are essential to prevent damage.

community Oral 1mg Finesteride 2mg Minoxidil

485 upvotes 3 months ago

The user experienced significant hair regrowth using 1mg finasteride and 2mg minoxidil daily, along with Nizoral shampoo and rosemary oil. They are curious about further improving hair density and whether increasing the minoxidil dose would help.

community What can be the real reason of Finasteride SE ?

18 upvotes 1 year ago

Finasteride can cause side effects like erectile dysfunction and decreased libido, possibly due to increased estradiol from testosterone aromatization, especially in those with higher body fat. Side effects vary widely and may also be influenced by genetic factors or neurosteroid inhibition.

community Realistically, how much PP405 will cost?

33 upvotes 1 year ago

PP405 is in phase 2 trials for hair loss, with discussions on its cost and effectiveness compared to minoxidil and finasteride. Users are skeptical about its efficacy and timeline, with hopes for market release by 2027.

community Rob English's scalp massages, why aren't more people aren't talking about this?

1 year ago

Rob English's scalp massages are discussed as a method to reduce DHT and stop hair loss, but many users criticize it as ineffective compared to treatments like finasteride, dutasteride, and minoxidil. Some users argue that alternative treatments like scalp massages and microneedling can work for some, but the community largely favors the "big three" medications.

View more "healing by secondary intention" in community →

Learn

2 / 801 results

learn Thymosin Beta 4

learn Neem Oil

natural substance from Neem tree with medicinal and pesticidal properties

View more "healing by secondary intention" in learn →

Clinics

4 / 5 results

Experts

— no results

Try a deeper search in experts →