September 2018 in “Fertility and Sterility” This study observed that inflammatory stimuli significantly altered gene expression in rat theca-interstitial cells, affecting pathways related to growth and androgen production, which are central features of polycystic ovary syndrome.
17 citations
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April 2009 in “Andrologia” This case study reports that hormonal imbalances in a young boy with precocious pseudopuberty returned to normal after the removal of a testicular interstitial cell tumor, with normal spontaneous puberty following.
Different drugs are used to manage breeding, prevent or end pregnancy, and treat reproductive issues in dogs and cats.
39 citations
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January 2019 in “The World Journal of Men's Health” Testosterone replacement therapy can prevent men from fathering children and should not be used by those wanting to stay fertile.
57 citations
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February 1983 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” This study found that pubic skin fibroblasts respond to androgens, increasing 5α-reductase activity via an androgen receptor-mediated mechanism, suggesting its potential as a marker of androgen action in vitro.