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African American women have a higher risk of preterm delivery than Caucasian women, and inflammatory stimuli affect gene expression in cells related to PCOS, showing a heightened inflammatory state in women with PCOS.

Using anabolic androgenic steroids can cause serious, lasting health problems in many parts of the body.

Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.

High levels of testosterone and anti-Müllerian hormone before pregnancy are linked to a higher risk of newborns needing intensive care.

Genetic defects in testosterone production can cause hormonal and developmental disorders, and more research is needed to understand androgen regulation and develop safer treatments.

The patient's high testosterone was reduced by a medication that suppresses gonadotropin.

New genes and pathways are important for testosterone production and male sexual development.

The L457(3.43)R mutation in the human lutropin receptor causes increased activity and hormone insensitivity, leading to precocious puberty.

Impaired androgen production in 46,XY DSDs causes ambiguous genitalia and requires long-term care.

Exposure to too much androgen before birth might cause polycystic ovary syndrome later in life.

High levels of male hormones, insulin resistance, and obesity are closely linked and worsen polycystic ovary syndrome, but more research is needed to improve treatments.

Hyperadrenocorticism in ferrets is linked to neutering and indoor housing, and is best treated with surgery and a deslorelin implant.

Melatonin receptors, found in many body parts, can help treat various diseases like depression and diabetes due to their effects on inflammation, tumor progression, sleep disorders, and body mass regulation.

HNG may help prevent the negative effects of chemotherapy on sperm production and white blood cell counts.

5α-reductase is essential for male sexual development and its inhibitors have potential in treating various conditions related to hormone action.

Excessive hair growth in women often has no known cause and is not linked to race or other hormonal symptoms.

The study found that women with hyperandrogenic PCOS have higher levels of AKT1 and AKT2 proteins in their cells, which may lead to cell dysfunction.

Oestrogens are key for bone growth during puberty in both boys and girls.

Estrogens are key for bone growth spurts in both boys and girls and affect growth into adulthood.

Early treatment of PCOS in teens is crucial to prevent long-term health issues like diabetes and heart disease.

Omega-6 fats in certain cells boost male hormone production.

A boy's early puberty caused by a testicular tumor returned to normal after surgery.

Dihydrotestosterone increases the activity of an enzyme in pubic skin cells that converts testosterone to dihydrotestosterone.

New treatments for male hypogonadism are effective and should be personalized.

Some supplements and hormones can increase hair loss by raising DHT levels.

Diagnosing sex development disorders requires combining medical history, physical exams, imaging, lab tests, and genetic data.

Different drugs are used to manage breeding, prevent or end pregnancy, and treat reproductive issues in dogs and cats.

A 19-year-old male with delayed puberty was successfully treated for a condition that prevents normal hormone production.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Gene mutations can cause problems in male genital development.