research Pantolactams as Androgen Receptor Antagonists for the Topical Suppression of Sebum Production
Pfizer found that pantolactam-based compounds can reduce sebum (skin oil) production when applied topically.
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research Comparison of Artificial Sebum with Human and Hamster Sebum Samples
Artificial sebum L closely mimics human sebum for drug delivery research.
research Anti-Acne Activity of Lipido-Sterolic Extract of Serenoa Repens and Hydro-Alcoholic Extract of Glycyrrhiza Glabra in Syrian Hamster Ear Model
Liquorice extract may help treat acne by reducing sebum production.
research Adrenal Steroid Precursors Exert Potent Androgenic Action in the Hamster Sebaceous Glands of Flank Organs and Ears
Certain adrenal hormones can strongly stimulate oil gland growth in hamster skin, similar to male hormones.
research Local and Systemic Reduction by Topical Finasteride or Flutamide of Hamster Flank Organ Size and Enzyme Activity
Topical finasteride and flutamide reduce gland size and enzyme activity, with flutamide being more potent, potentially treating acne, seborrhea, hirsutism, and androgenic alopecia.
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5 / 6 resultscommunity Surprise Hair Loss Breakthrough: A Sugar Gel Triggers Robust Regrowth
A sugar gel was claimed to trigger hair regrowth, but users reported no results and potential cancer risks. The discussion included comparisons to minoxidil and skepticism about the effectiveness of the sugar treatment.
community Minoxidil is NOT an Anti-androgen. No.
Minoxidil is not an anti-androgen; it is a growth stimulator and does not lower DHT like finasteride or dutasteride. Minoxidil can cause side effects like facial swelling and anxiety due to its vasodilator properties.
community Why a lot of people seems to hate on topical fin even though it suppresses more scalp dht?
Topical finasteride may reduce more scalp DHT but is seen as inconsistent and messy compared to oral finasteride. Users report mixed results with both forms, with some preferring oral for its convenience and consistent dosing, while others find topical effective but harder to apply.
community 1 year and 3 months on Finasteride. No side effects.
A user happy with their 1 year and 3 months of finasteride use with no side effects, which has resulted in recovery of their hairline. Other users have responded with congratulations, questions, and caution against using the medication at such a young age.
community Finastride hair texture change is wild
Finasteride changed the user's hair texture from wavy to curly, reverting after stopping. Minoxidil was more effective for temple hair regrowth than finasteride.