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research The trichoscopic features of hair shaft anomalies induced by epidermal growth factor receptor inhibitors: A case series

7 citations , March 2020 in “Journal of the American Academy of Dermatology”

This study observed that trichoscopic changes associated with EGFRI treatment include pili torti and asymmetric hyperpigmented fusiform widening, along with dermoscopic skin manifestations such as scale and branching vessels.

research Bubble hair and other acquired hair shaft anomalies due to hot ironing on wet hair

15 citations , January 2011 in “International journal of trichology”

This report describes a classic case of bubble hair, an acquired hair shaft abnormality, in a 22-year-old woman after using a hot iron on wet hair.

research AN UPDATE OF HAIR SHAFT DISORDERS

12 citations , October 1996 in “Dermatologic clinics”

This review outlines the diagnostic criteria for congenital and hereditary hair shaft abnormalities and emphasizes the need to understand the weathering process in assessing these disorders.

research Hair Anomalies in a 6-Year-Old Girl

January 2016 in “Case reports in clinical medicine”

This article discusses monilethrix in a 6-year-old girl, explores various aspects of the disease, and its treatment, but reports no new clinical results.

research Congenital hair loss disorders: Rare, but not too rare

41 citations , November 2011 in “The Journal of Dermatology”

This review identifies genetic mutations associated with congenital hair loss disorders in Japanese populations, particularly highlighting common LIPH gene mutations linked to woolly hair/hypotrichosis, and reports no new clinical results.

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Community Join

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community Cbum's hair transplant looks absolutely terrible

979 upvotes 1 year ago

A bodybuilder's hair transplant appears unnatural with a straight hairline and low density, possibly worsened by not using finasteride. The Turkish clinic is criticized for poor design, and the transplant may have been free for promotion.

community Hair Shaft Diameter and Density Comparison

13 upvotes 4 weeks ago

The conversation discusses differences in hair shaft diameter and density between thinning and denser areas on the scalp. Treatments mentioned include Minoxidil, finasteride, and dutasteride.

community FDA Policy Shift Explained: What It Actually Means for PP405, VDPHL-01, Breezula and Hair Loss Drug Timelines

in Research/Science 42 upvotes 6 months ago

The FDA policy change may speed up approval for hair loss drugs like PP405, VDPHL-01, and Breezula by potentially eliminating the need for a second confirmatory Phase 3 trial. Approval timelines could be as early as 2028 for some treatments if Phase 3 results are strong.

community Recent trials investigating mesenchymal stem cell derived exosomes demonstrate significant increases in anagen duration and hair shaft caliber by upregulating Wnt/beta-catenin pathways.

4 upvotes 3 weeks ago

Exosomes from mesenchymal stem cells can increase hair growth by enhancing anagen duration and hair shaft thickness through the Wnt/beta-catenin pathway. Phase 2 trials show improved hair counts over 24 weeks.

community Microneedling must reach the stem cells in the upper hair shaft

82 upvotes 4 years ago

Microneedling should target depths of 0.5mm to 1.5mm for hair loss, with weekly sessions at 1mm recommended. Combining microneedling with Minoxidil is common for improved results.

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Learn

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learn Cetirizine

How does cetirizine reduce inflammation linked to hair loss? Cetirizine is proposed to lower prostaglandin D2 and raise prostaglandin E2 around hair follicles; three small trials of a compounded 1% topical report modest increases in hair density and shaft thickness, with minoxidil doing better head-to-head. Topical cetirizine is off-label and unapproved for hair loss, and the evidence is too thin to call it effective or safe.

learn Hair Multiplication

extract, clone, and reinsert your own hair cells

learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

learn Adenosine

nucleoside used for hair regrowth stimulant properties

learn Valproic acid

an anticonvulsant repurposed for hair loss via histone inhibition

learn Stemoxydine

chemical from L'Oreal that encourages hair to enter growth phase

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Clinics

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Experts

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SMP Specialist
Hairo Fallas
Newark, NJ, United States

Hairo Fallas