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research INTRODUCING THEORY LINKING GENESIS OF HAIR SHAFT BIPOLARITY WITH ARRECTOR PILI MUSCLE PROXIMAL ATTACHMENT

November 2021 in “International journal of research - granthaalayah”

This study presents additional data suggesting that the absence of nerve endings in certain segments of human hair follicles influences the asymmetrical distribution of electrical charges, as indicated by no precipitation of Potassium Ferricyanide crystals.

research Comparative Studies of the Diameters of Hairshafts in Anagen and in Telogen Phases in Male Adults Without Alopecia and in Male Adults With Androgenetic Alopecia

6 citations , January 1981

research Hair distribution width – a novel trichoscopy parameter for hair miniaturization in androgenetic alopecia

1 citations , May 2019 in “Journal of The European Academy of Dermatology and Venereology”

New method, hair distribution width (HDW), improves accuracy in diagnosing androgenetic alopecia (AGA).

research Association of Topical Minoxidil With Autosomal Recessive Woolly Hair/Hypotrichosis Caused by LIPH Pathogenic Variants

5 citations , July 2020 in “JAMA Dermatology”

Minoxidil solution applied twice daily improved hair growth in patients with Woolly Hair/Hypotrichosis due to LIPH gene issues, with mild side effects.

Comparison of Efficacy of Platelet-Rich Plasma With and Without Topical Minoxidil for Hair Growth in Patients With Androgenetic Alopecia: A Prospective Study

research Comparison of Efficacy of Platelet-Rich Plasma With and Without Topical Minoxidil for Hair Growth in Patients With Androgenetic Alopecia: A Prospective Study

February 2024 in “Cureus”

This study found that combining platelet-rich plasma therapy with topical minoxidil improved hair shaft diameter and hair follicle density more effectively than PRP alone in men with androgenetic alopecia.

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Community Join

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community Losing hair without the white bulb, Tressless GPT's Response. Do you guys agree?

4 upvotes 1 year ago

Hair loss without a white bulb may indicate mechanical damage, anagen effluvium, alopecia areata, or traction alopecia. Seeking a specialist is recommended, but access can be difficult in smaller areas.

community The new growth in hair loss research: With increasing evidence of its impact on mental health, scientists are pushing forward with breakthroughs on balding. Later this year, scientists will launch one of the first ever clinical trials with hair follicles grown entirely from stem cells.

324 upvotes 7 years ago

Hair loss impacts mental health, with treatments like Minoxidil, finasteride, and stem cell transplants discussed. There is hope for future breakthroughs, but current treatments are limited, and awareness is lacking.

community FDA Policy Shift Explained: What It Actually Means for PP405, VDPHL-01, Breezula and Hair Loss Drug Timelines

in Research/Science 42 upvotes 6 months ago

The FDA policy change may speed up approval for hair loss drugs like PP405, VDPHL-01, and Breezula by potentially eliminating the need for a second confirmatory Phase 3 trial. Approval timelines could be as early as 2028 for some treatments if Phase 3 results are strong.

community Dutasteride switch after 8 months made my hair worse (With picture proof)

in Research/Science 62 upvotes 1 year ago

Switching to Dutasteride worsened hair condition, causing shedding and inflammation. The user will continue Dutasteride until 18 months before possibly switching back to Finasteride, while using oral Minoxidil.

community Recent trials investigating mesenchymal stem cell derived exosomes demonstrate significant increases in anagen duration and hair shaft caliber by upregulating Wnt/beta-catenin pathways.

4 upvotes 4 weeks ago

Exosomes from mesenchymal stem cells can increase hair growth by enhancing anagen duration and hair shaft thickness through the Wnt/beta-catenin pathway. Phase 2 trials show improved hair counts over 24 weeks.

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Learn

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learn Hair Multiplication

extract, clone, and reinsert your own hair cells

learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

learn Adenosine

nucleoside used for hair regrowth stimulant properties

learn Stemoxydine

chemical from L'Oreal that encourages hair to enter growth phase

learn HMI-115

much-hyped research compound targeting prolactin receptor in scalp

learn Cetirizine

How does cetirizine reduce inflammation linked to hair loss? Cetirizine is proposed to lower prostaglandin D2 and raise prostaglandin E2 around hair follicles; three small trials of a compounded 1% topical report modest increases in hair density and shaft thickness, with minoxidil doing better head-to-head. Topical cetirizine is off-label and unapproved for hair loss, and the evidence is too thin to call it effective or safe.

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