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Overexpression of Cyclooxygenase-2 in the Skin of Adult Transgenic Mice Leads to Sebaceous Gland Hyperplasia and Thinning of Hair Shafts

research 919 Overexpression of cyclooxygenase-2 in the skin of adult transgenic mice leads to sebaceous gland hyperplasia and thinning of hair shafts

April 2019 in “Journal of Investigative Dermatology”

This study found that induced COX-2 expression in adult transgenic mice led to hair follicle miniaturization and enlargement of sebaceous glands, and suggests that targeting the PGD2 pathway might reverse these effects.

research Isolation and Quantification of Glycosaminoglycans from Human Hair Shaft

6 citations , January 2016 in “Annals of Dermatology”

This study found that glycosaminoglycan levels were higher in the occipital area of the hair shaft compared to the parietal area, with children showing higher levels than adults.

research Suprabulbar Thinning of Hair in Telogen Effluvium

1 citations , January 2017 in “Yonsei Medical Journal”

Hair is thinner near the scalp in acute hair shedding conditions.

A Nonrandomized Study of Trichoscopy Patterns Using Nonpolarized (Contact) and Polarized (Noncontact) Dermatoscopy in Hair and Shaft Disorders

research A Nonrandomized study of trichoscopy patterns using nonpolarized (contact) and polarized (noncontact) dermatoscopy in hair and shaft disorders

34 citations , January 2014 in “International Journal of Trichology”

This study reported that polarized dermoscopy was better for visualizing vascular patterns, scaling, and reticular pigmentation, while nonpolarized mode better documented features like black dots and tapered hair in various hair and scalp conditions.

research Perception of Baldness and Hair Density

16 citations , January 2002 in “Dermatology”

This study found that the parietal/occipital hair density ratio decreases significantly only when baldness is visibly present, making it no better than the Hamilton/Norwood scale for assessing baldness severity.

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Community Join

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community Hair Shaft Diameter and Density Comparison

13 upvotes 3 weeks ago

The conversation discusses differences in hair shaft diameter and density between thinning and denser areas on the scalp. Treatments mentioned include Minoxidil, finasteride, and dutasteride.

community i was thinking of gettin full head wig that way i get hair and a beard and perfect skin

in Satire 389 upvotes 1 year ago

The conversation humorously discusses using a full head wig for hair, beard, and perfect skin, with mentions of treatments like finasteride, RU58841, and microneedling. It highlights a shift from serious hair loss discussions to satire and memes.

community Im shedding more short hairs??

in Is this regrowth? 1 upvotes 2 years ago

A 16-year-old experiencing hair thinning noticed a shift from shedding long hairs to shorter hairs, while using Vitamin D, biotin supplements, ketoconazole shampoo, and improving diet. They are questioning if the short hairs indicate regrowth or androgenetic alopecia (AGA).

community Hair thinning after 40 is destroying my confidence need a hair growth supplement.

in Treatment 17 upvotes 1 month ago

A 47-year-old experiencing hair thinning likely due to perimenopause is advised to consider treatments like minoxidil, finasteride, and supplements such as saw palmetto. Blood tests for iron, thyroid, and vitamin levels are recommended, and options like estrogen replacement therapy and hair growth supplements are discussed.

community Best disguise I’ve found so far for my awful thinning balding hair?!

330 upvotes 1 month ago

Bleaching hair can disguise thinning and balding by reducing contrast with the scalp, providing a temporary aesthetic solution. The user is also using finasteride and oral minoxidil for hair regrowth.

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Learn

6 / 66 results

learn Hair Multiplication

extract, clone, and reinsert your own hair cells

learn Adenosine

nucleoside used for hair regrowth stimulant properties

learn Stemoxydine

chemical from L'Oreal that encourages hair to enter growth phase

learn GHK-Cu

a copper peptide showing promise in both regrowth and reversing gray hair

learn HMI-115

much-hyped research compound targeting prolactin receptor in scalp

learn Cetirizine

How does cetirizine reduce inflammation linked to hair loss? Cetirizine is proposed to lower prostaglandin D2 and raise prostaglandin E2 around hair follicles; three small trials of a compounded 1% topical report modest increases in hair density and shaft thickness, with minoxidil doing better head-to-head. Topical cetirizine is off-label and unapproved for hair loss, and the evidence is too thin to call it effective or safe.

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Clinics

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Experts

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SMP Specialist
Hairo Fallas
Newark, NJ, United States

Hairo Fallas