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Did you mean Hair Shaft Structure?

Glossary Hair Shaft Structure

three main layers of a hair strand: cuticle, cortex, medulla

The hair shaft structure refers to the three main layers of a hair strand: the cuticle, cortex, and medulla. The cuticle is the outermost layer, made of overlapping cells that protect the inner layers. The cortex, which is the thickest layer, contains keratin and pigments that give hair its strength, color, and texture. The medulla, found in thicker hair types, is the innermost layer and consists of a soft, spongy core. Understanding these layers is crucial for diagnosing hair conditions and developing effective hair care treatments.

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Research

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research Hair shaft structures in EDAR induced ectodermal dysplasia

5 citations , September 2015 in “BMC Medical Genetics”

In this study, individuals with a c.1072C > T mutation in the EDAR gene showed more hair shaft deformations compared to non-mutation carriers, highlighting EDAR's role in hair follicle development.

Sample Collecting Methods for Bacterial Community Structure Analysis of Scalp Hair: Non-Invasive Swabbing Versus Intrusive Hair Shaft Cutting

research Sample collecting methods for bacterial community structure analysis of scalp hair: non-invasive swabbing versus intrusive hair shaft cutting

1 citations , September 2024 in “Scientific Reports”

This study observed that bacterial communities on scalp hair collected through non-invasive swabbing showed similar diversity and composition to those obtained by cutting or removing hair, suggesting that swabbing is an effective method for microbiome analysis on hair.

research Adverse reaction to isotretinoin: alteration of the hair shaft structure

January 2022 in “Surgical & Cosmetic Dermatology”

This case report described a rare instance of new curly hair growth in a patient undergoing isotretinoin treatment for acne vulgaris, highlighting the potential for isotretinoin to alter hair fiber curvature.

research Distribution of bacterial community structures on human scalp hair shaft in relation to scalp sites

September 2023 in “Bioscience, biotechnology, and biochemistry”

In this study, researchers observed that bacterial community structures on human scalp hair are unique to individuals and show consistent patterns across different sampling sites on the scalp, without significant variation between these sites.

research Hair care practices and structural evaluation of scalp and hair shaft parameters in African American and Caucasian women

25 citations , August 2015 in “Journal of cosmetic dermatology”

This study observed significant differences in hair care practices and biologic hair parameters between Caucasian and African American women, which may contribute to varying hair fragility and growth.

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Community Join

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community FDA Policy Shift Explained: What It Actually Means for PP405, VDPHL-01, Breezula and Hair Loss Drug Timelines

in Research/Science 42 upvotes 6 months ago

The FDA policy change may speed up approval for hair loss drugs like PP405, VDPHL-01, and Breezula by potentially eliminating the need for a second confirmatory Phase 3 trial. Approval timelines could be as early as 2028 for some treatments if Phase 3 results are strong.

community New study suggests hair regrowth on wounded and bald skin may be possible

4 upvotes 7 years ago

Hair regrowth on wounded and bald skin may be possible by activating the sonic hedgehog gene, leading to hair regrowth in mice. The findings are promising but may not directly apply to humans.

community What Are the Technicalities of Curved Hair Transplantation?

4 upvotes 5 months ago

Curved hair transplantation requires specialized tools and techniques to avoid damaging hair follicles, with modified FUE being the preferred method. Proper extraction and implantation angles are crucial to prevent complications like keloids and sterile folliculitis.

community Hair loss research focused on chemistry for decades because we misunderstood the mechanics of growth.

51 upvotes 7 months ago

Hair growth relies on mechanical forces, not just chemicals, with tissue acting like a motor. Minoxidil and finasteride help, but maintaining tissue elasticity and addressing mechanical issues are essential.

community End of Hair loss ( AGA ) ? Since they produce it in china probably we don’t need to wait other 10 yrs😁

276 upvotes 6 months ago

GT20029 is a new hair loss treatment in Phase 3 trials in China, using PROTAC technology to target androgen receptors, potentially with fewer side effects than finasteride and minoxidil. VDPHL01, a second-generation minoxidil, is also mentioned as potentially more effective.

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Learn

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learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

learn GHK-Cu

a copper peptide showing promise in both regrowth and reversing gray hair

learn Epidermal Growth Factor

learn Thymosin Beta 4

learn Stem Cell Factor

learn Cetirizine

How does cetirizine reduce inflammation linked to hair loss? Cetirizine is proposed to lower prostaglandin D2 and raise prostaglandin E2 around hair follicles; three small trials of a compounded 1% topical report modest increases in hair density and shaft thickness, with minoxidil doing better head-to-head. Topical cetirizine is off-label and unapproved for hair loss, and the evidence is too thin to call it effective or safe.

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Clinics

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SHIFT Hair TRİstanbul · TR

Experts

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SMP Specialist
Hairo Fallas
Newark, NJ, United States

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Hairo Fallas