This study utilized polarized light microscopy to examine hairshafts in ten children with rare genetic disorders, such as Netherton syndrome and ectodermal dysplasia, providing valuable diagnostic insights into hair thickness, composition, and structural irregularities associated with these conditions.
1 citations
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November 2022 in “DOAJ (DOAJ: Directory of Open Access Journals)”
This study found that male and female hair specimens show structural differences, with female hair having a brown color at the distal end and smooth surface texture, while male hair is completely black and shows surface irregularities; these differences may aid forensic analysis.
23 citations
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July 1994 in “Journal of Dermatological Science”
This study found that the twisted hairshafts characteristic of pili torti may result from uneven outer root sheath cell development, leading to irregular hairshaft modeling and twisting.
A user shared impressive hair regrowth results after three months of taking 1mg daily of finasteride. Other users commented on their experiences and the effectiveness of different treatments like minoxidil and dutasteride.
The conversation discusses differences in hairshaft diameter and density between thinning and denser areas on the scalp. Treatments mentioned include Minoxidil, finasteride, and dutasteride.
The FDA policy change may speed up approval for hair loss drugs like PP405, VDPHL-01, and Breezula by potentially eliminating the need for a second confirmatory Phase 3 trial. Approval timelines could be as early as 2028 for some treatments if Phase 3 results are strong.
Exosomes from mesenchymal stem cells can increase hair growth by enhancing anagen duration and hairshaft thickness through the Wnt/beta-catenin pathway. Phase 2 trials show improved hair counts over 24 weeks.
Mesotherapy with dutasteride significantly improves hair density, thickness, and quality in female pattern hair loss with minimal side effects. The treatment strengthens hair cuticles by reducing DHT through 5AR inhibition.
How does cetirizine reduce inflammation linked to hair loss?Cetirizine is proposed to lower prostaglandin D2 and raise prostaglandin E2 around hair follicles; three small trials of a compounded 1% topical report modest increases in hair density and shaft thickness, with minoxidil doing better head-to-head. Topical cetirizine is off-label and unapproved for hair loss, and the evidence is too thin to call it effective or safe.