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      Polarized Microscopy in Genetic Hair Disorders: Case Series

      research Polarized microscopy in genetic hair disorders: case series

      January 2025
      This study utilized polarized light microscopy to examine hair shafts in ten children with rare genetic disorders, such as Netherton syndrome and ectodermal dysplasia, providing valuable diagnostic insights into hair thickness, composition, and structural irregularities associated with these conditions.
      Comparative Study of Male and Female Human Hair: A Microscopic Analysis

      research Comparative study of male and female human hair: A microscopic analysis.

      1 citations , November 2022 in “DOAJ (DOAJ: Directory of Open Access Journals)”
      This study found that male and female hair specimens show structural differences, with female hair having a brown color at the distal end and smooth surface texture, while male hair is completely black and shows surface irregularities; these differences may aid forensic analysis.
      Structural Abnormalities of the Hair Shaft

      research Structural abnormalities of the hair shaft

      126 citations , January 1987 in “Journal of The American Academy of Dermatology”
      This article reviews the classification of hair shaft abnormalities, outlining their diagnostic features, but does not present new research findings.

      research Pathogenesis in pili torti: morphological study

      23 citations , July 1994 in “Journal of Dermatological Science”
      This study found that the twisted hair shafts characteristic of pili torti may result from uneven outer root sheath cell development, leading to irregular hair shaft modeling and twisting.

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      learn Cetirizine

      • How does cetirizine reduce inflammation linked to hair loss? Cetirizine is proposed to lower prostaglandin D2 and raise prostaglandin E2 around hair follicles; three small trials of a compounded 1% topical report modest increases in hair density and shaft thickness, with minoxidil doing better head-to-head. Topical cetirizine is off-label and unapproved for hair loss, and the evidence is too thin to call it effective or safe.

      learn Osteopontin

      signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

      learn Adenosine

      nucleoside used for hair regrowth stimulant properties

      learn Valproic acid

      an anticonvulsant repurposed for hair loss via histone inhibition

      learn Stemoxydine

      chemical from L'Oreal that encourages hair to enter growth phase