37 citations
,
June 2000 in “Experimental dermatology”
This study investigated a spontaneous mutation in mice resulting in hair abnormalities and elevated IgE levels, which resembles human Netherton's syndrome and monilethrix.
April 2025 in “Indian Journal of Paediatric Dermatology”
This case report describes an 8-year-old male with tinea capitis and Trichorrhexis invaginata, who showed significant improvement after treatment with oral micronized griseofulvin.
68 citations
,
August 2012 in “Journal of the American Academy of Dermatology”
This paper discusses the use of dermatoscopy as a fast, noninvasive technique for diagnosing hairshaft disorders and reports no new results; the authors highlight its advantages over traditional microscopy methods.
36 citations
,
August 2018 in “Dermatologic Clinics”
This article reviews various hair abnormalities observable through trichoscopy in conditions like monilethrix, trichorrhexis nodosa, and ectodermal dysplasias, with no new clinical findings reported.
A 44-year-old user experienced hair regrowth using a topical spray combining 0.3% finasteride and 7% minoxidil after switching from oral finasteride due to side effects. The user reported noticeable improvements in hair thickness after four months without any side effects from the topical treatment.
A 26-year-old man embraced baldness, gaining confidence and personal growth, and encourages self-acceptance. Others discussed hair loss treatments like Minoxidil and finasteride, but he did not use them.
The conversation discusses differences in hairshaft diameter and density between thinning and denser areas on the scalp. Treatments mentioned include Minoxidil, finasteride, and dutasteride.
The FDA policy change may speed up approval for hair loss drugs like PP405, VDPHL-01, and Breezula by potentially eliminating the need for a second confirmatory Phase 3 trial. Approval timelines could be as early as 2028 for some treatments if Phase 3 results are strong.
How does cetirizine reduce inflammation linked to hair loss?Cetirizine is proposed to lower prostaglandin D2 and raise prostaglandin E2 around hair follicles; three small trials of a compounded 1% topical report modest increases in hair density and shaft thickness, with minoxidil doing better head-to-head. Topical cetirizine is off-label and unapproved for hair loss, and the evidence is too thin to call it effective or safe.