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research Melanocyte stem cells: a melanocyte reservoir in hair follicles for hair and skin pigmentation

240 citations , April 2011 in “Pigment Cell & Melanoma Research”

This review discusses the identification and characteristics of melanocyte stem cells, emphasizing their role in hair pigmentation, greying, and skin repigmentation, but reports no new research findings.

research Unlocking Hair Follicles as Drug Reservoirs: Advances in Transfollicular Drug Delivery

April 2026 in “Zenodo (CERN European Organization for Nuclear Research)”

This review highlights advancements in transfollicular drug delivery, noting that nanoparticles optimized to 300-400nm improve drug penetration into hair follicles better than conventional formulations, and that novel stimulus-responsive systems offer enhanced targeted delivery for conditions like androgenic alopecia and acne.

research Is there a relationship between premature gray hair and other autoimmune phenomena with diminished ovarian reserve?

August 2012 in “Fertility and Sterility”

Premature gray hair may indicate reduced ovarian reserve but doesn't lower pregnancy chances.

research The Human Hair Follicle: A Reservoir of CD40+ B7-Deficient Langerhans Cells that Repopulate Epidermis After UVB Exposure

99 citations , April 1998 in “The journal of investigative dermatology/Journal of investigative dermatology”

This study found that human hair follicles serve as a crucial reservoir for Langerhans cells, which repopulate the epidermis depleted by ultraviolet B exposure.

research Human hair follicle: reservoir function and selective targeting

97 citations , September 2011 in “British Journal of Dermatology”

The human hair follicle can store topical compounds and be targeted for drug delivery with minimal side effects.

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community 1 year before/after 3500 graft hair transplant

116 upvotes 1 week ago

A 31-year-old male shared his experience with a 3500 graft hair transplant and plans for a second procedure, using treatments like dutasteride, minoxidil, a red light hat, and Nizoral. He clarified that hair transplants can be done for diffuse thinning and discussed future maintenance and graft reserves.

community Update 1.5 years on finasteride. My experience so far.

in Progress Pictures 265 upvotes 1 year ago

The user experienced initial hair regrowth using finasteride, minoxidil, and a dermaroller but faced setbacks after a treatment break and dry scalp issues. They are considering switching treatments and have added ketoconazole shampoo and reservatol plus to their regimen.

community New Breezula Update ( I think)

18 upvotes 10 months ago

Breezula's phase 3 enrollment for hair loss treatment is complete, but results have not been published, causing skepticism about its progress. Some users express doubt about its future, suggesting it may be reserved for exclusive use.

community Proof DHT is not the main cause of hair loss. TRPS1 Gene and Protein might be. PP405 won’t work. AMP-303 might!

153 upvotes 6 months ago

Hair loss may be linked to the TRPS1 gene and protein, not just DHT. Amplifica's AMP-303 targets mesenchymal stem cells and shows promise in treating hair loss, unlike Pelage's PP405.

community Spending $10K on a hair transplant in the U.S. vs $5,000 for one in Turkey

2214 upvotes 1 year ago

Hair transplants cost more in the U.S. than in Turkey, but quality varies. Proper research is essential, as aggressive transplants can exhaust donor hair, and finasteride only slows hair loss.

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