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Paracrine Secreted Frizzled-Related Protein 4 Inhibits Melanocyte Differentiation in Hair Follicle

research Paracrine Secreted Frizzled-Related Protein 4 Inhibits Melanocytes Differentiation in Hair Follicle

8 citations , January 2017 in “Stem Cells International”

This study found that overexpression of sFRP4 in skin cells reduces Wnt signaling activation, leading to decreased melanocyte differentiation in regenerating hair follicles.

research Secreted Frizzled-related protein 4 inhibits the regeneration of hair follicles

7 citations , January 2019 in “PeerJ”

This study found that intradermal injection of Secreted Frizzled-related Protein 4 inhibits, but does not block, hair follicle regeneration in mice, suggesting potential therapeutic applications for hair follicle regeneration disorders.

Follistatin and Secreted Frizzled-Related Protein 1, OVOL1-Regulated Genes, Are Important for Hair Follicle Neogenesis

research Follistatin and secreted frizzled-related protein 1, OVO homolog-like 1-regulated genes, are important for hair follicle neogenesis

4 citations , April 2015 in “Experimental Dermatology”

This study found that OVOL1-regulated genes, particularly Fst and SFRP1, significantly affect the hair-inducing capacity of neonatal mouse dermal cells.

Peer Review of Secreted Frizzled-Related Protein 4 Inhibits the Regeneration of Hair Follicles

research Peer Review #2 of "Secreted Frizzled-related protein 4 inhibits the regeneration of hair follicles (v0.1)"

January 2019

This study found that sFRP4 inhibits but does not block hair follicle regeneration in mice, suggesting a potential role in treating hair follicle regeneration disorders.

Peer Review of Secreted Frizzled-Related Protein 4 Inhibiting Hair Follicle Regeneration

research Peer Review #1 of "Secreted Frizzled-related protein 4 inhibits the regeneration of hair follicles (v0.1)"

January 2019

This study found that injecting sFRP4 into mouse skin partially inhibited hair follicle regeneration, suggesting a potential therapy for hair follicle regeneration disorders.

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Community Join

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community Frizzy hair what products should I use?

2 upvotes 2 years ago

The user is seeking advice for frizzy hair, having tried coconut oil without success and considering Olaplex products. They are looking for effective product recommendations.

community Do dut and fin reduce sebum causing frizzy hair?

in Finasteride/Dutasteride 6 upvotes 5 months ago

The user is experiencing dry, frizzy hair despite using dutasteride and finasteride for hair loss, which may be due to reduced sebum production. Suggestions include using nourishing conditioners, hair oils, and styling products to manage frizz, especially for curly hair.

community Is it safe to get keratin treatment on transplanted hair?

2 upvotes 2 years ago

A user with frizzy transplanted hair is considering a keratin treatment after 10 months and is concerned about its safety and potential to accelerate hair loss or cause telogen effluvium. They are seeking advice on whether it is safe to proceed with the treatment.

community can we talk about the effect of DHT on hair TEXTURE (not just thickness/density)

41 upvotes 1 month ago

Finasteride treatment improved hair texture and reduced frizz for some users, though full restoration of original texture may take time. Hair texture changes were noted across the head, with some areas responding faster to treatment.

community How come some guys are half bald yet their hair is so healthy?

in Finasteride/Dutasteride 62 upvotes 1 year ago

A 22-year-old male experiencing diffuse thinning and frizzy hair has been using finasteride for nine months and is seeking advice on improving hair quality. Suggestions include using conditioners, biotin, rosemary oil, and addressing scalp conditions like seborrheic dermatitis or psoriasis, while finasteride may help reverse miniaturization and improve hair health.

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Clinics

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Learn

3 / 801 results

learn Hair Fibers

cosmetic product that temporarily makes hair appear thicker

Do hair fibers really make thinning hair look fuller, or is it just an illusion? Hair fibers create an optical illusion of fullness but do not actually thicken hair.
How do you apply hair fibers correctly so they stay in place all day? Apply hair fibers to clean, dry hair and use a setting spray for better hold.
Can hair fibers be used along with medical treatments like minoxidil or finasteride? Yes, hair fibers can be used with minoxidil or finasteride without any chemical interaction.
All 5 questions on Hair Fibers →

learn Hair Multiplication

extract, clone, and reinsert your own hair cells

learn Hair Transplant

Hair transplantation moves DHT-resistant follicles from a donor area (back and sides of the scalp) into thinning or bald areas. The transplanted hair is generally permanent, though surrounding native hair can keep thinning.

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Experts

1 / 17 results

Unscored
SMP Specialist
Hairo Fallas
Newark, NJ, United States

Hairo Fallas