2 citations
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February 2020 in “Journal of Plastic Surgery and Hand Surgery”
This study found that donor sites with higher hairdensity and thicker hair diameter had a better appearance after follicular unit excision in men with androgenic alopecia.
October 2025 in “Journal of Pharmacy And Bioallied Sciences”
This study concluded that platelet-rich plasma significantly improves hairdensity and patient satisfaction for individuals undergoing follicular unit extraction for androgenetic alopecia compared to those receiving the surgery alone.
This study found that new methods for isolating human dermal papilla cells were more efficient than traditional methods, maintaining higher levels of specific markers and improving the cells' research potential.
PP405, a topical treatment, shows promise for hair growth by activating inactive follicles, with 66% of participants experiencing positive results. The treatment is well-tolerated and may proceed directly to Phase 3 trials, offering a potential alternative to minoxidil and finasteride.
Taking oral Vitamin D alongside topical minoxidil improves hairdensity more than using minoxidil alone. Users discuss Vitamin D dosages, potential benefits, and the importance of combining it with Vitamin K2.
The user had two FUT hair transplants with 4,600 grafts for increased density, costing about $11,000 each, and has been using oral minoxidil and finasteride for over five years without side effects. The results are natural-looking with no visible scarring, and the user finds the procedure valuable despite the cost.
A user recommends using a microscope to assess hairdensity and track hair loss progress, finding it useful for evaluating treatment effectiveness, particularly with dutasteride and minoxidil. They advise against obsessing over hair loss and emphasize focusing on other meaningful life aspects.
PP405 shows promise in hair regrowth, with 31% of participants experiencing over 20% increase in hairdensity after 8 weeks. Phase 3 trials are expected in 2026, with potential market availability by 2029-2031.
Alfatradiol: Can it help if my hair loss is linked to DHT?The one randomised trial of topical alfatradiol — in 103 women — found hair thickness and density essentially unchanged after six months, while minoxidil improved both; its authors credited alfatradiol with slowing hair loss rather than regrowing hair. Laboratory work supports a local effect on follicular DHT, but no controlled trial in men appears to have been published.