Search

for
Search:

Research

5 / 1000+ results

research 872 Dermal Wnt/β-catenin signaling controls hair follicle dermal condensate size during development

April 2017 in “Journal of Investigative Dermatology”

This study suggests that dermal Wnt/β-catenin activation timing is crucial for hair follicle initiation, with potential non-cell autonomous regulation of dermal condensate size.

research 1338 Dermal Wnt/β-catenin activation tunably controls hair follicle initiation

May 2018 in “Journal of Investigative Dermatology”

Activating Wnt in skin cells controls the number of hair follicles by directing cell movement and fate.

research A single-cell transcriptome atlas during Cashmere goat hair follicle morphogenesis

1 citations , January 2020 in “bioRxiv (Cold Spring Harbor Laboratory)”

This study provided a detailed molecular profile of Cashmere goat hair follicle development using single-cell RNA sequencing, revealing unique cell populations and conserved developmental programs compared to mouse models.

research The origins of skin diversity: lessons from dermal fibroblasts

6 citations , November 2022 in “Development”

This review discusses the developmental origins and diversity of dermal fibroblasts, focusing on their roles in epidermal and hair follicle growth, but reports no clinical results.

research 1362 The role of Fgf20 in establishing the hair follicle dermal condensate

April 2018 in “Journal of Investigative Dermatology”

This study found that Fgf20 signaling facilitates fibroblast migration and influences dermal condensate cell development during hair follicle morphogenesis by supporting cellular activities such as cell cycle exit and specific cell shape adoption.

View more "hair follicle dermal condensate lineage" in research →

Learn

6 / 801 results

learn Stem Cell Factor

learn SCUBE3

a signaling molecule from dermal papilla cells being actively researched

How does SCUBE3 work on hair follicles compared to treatments like minoxidil or finasteride? Laboratory research in mice reports that SCUBE3, a protein released by dermal papilla cells, signals dormant follicles to grow through the TGF-β pathway downstream of Hedgehog; minoxidil and finasteride instead work on blood flow to the follicle and on DHT, and unlike SCUBE3 they have decades of human trial data behind them. SCUBE3 has not been tested in human clinical trials and is not available as a medicine.

learn Platelet-Rich Plasma

What is Platelet-Derived Growth Factor Beta Polypeptide, and how does it help stimulate new hair growth? PDGF-BB is a growth factor that signals to dermal papilla cells and promotes blood-vessel formation; mouse studies report it can push follicles into the growth phase, and human evidence comes only indirectly from PRP trials. No PDGF product is approved for hair restoration and there is no published human trial of PDGF-BB on its own.

learn Hair Multiplication

extract, clone, and reinsert your own hair cells

learn Exosomes

Microscopic delivery system that sends growth-promoting signals to hair follicles

learn KY19382

compound that activates Wnt/β-catenin to promote hair regrowth and create new hair follicles

View more "hair follicle dermal condensate lineage" in learn →

Community Join

5 / 1000+ results

community 4 months update (fin + min + derma stamps)

in Progress Pictures 644 upvotes 1 year ago

The user shared a 4-month update on hair loss treatment using finasteride, minoxidil, and derma stamps, showing significant progress. The user experienced no side effects and plans to continue the treatment, updating monthly.

community Prolactin the Cause of Hair Loss? ABS-201 the Cure?

29 upvotes 2 months ago

Prolactin may contribute to hair loss, but targeting its receptor won't cure androgenetic alopecia. ABS-201 could be a useful alternative or adjuvant therapy, similar to JAK inhibitors, but not more effective than HMI-115.

community When Life Starts Taking Your Hair... And Then Your Confidence: A 25-Year-Old’s Battle with Hair Loss

in Chat 124 upvotes 1 year ago

A 25-year-old discusses hair loss and its impact on confidence, considering treatments like finasteride and minoxidil. Recommendations include these medications and lifestyle changes to manage hair loss.

community Yes, your hair CAN get worse on dutasteride and fin DOES work better for some (With pictures over 1.5 years)

219 upvotes 1 year ago

Switching from finasteride to dutasteride can worsen hairlines for some, as experienced by the original poster. Finasteride worked better for them, and they suggest returning to it if dutasteride causes hair loss.

community The Cure isn't 5 years away; it's already here.

in Research/Science 1005 upvotes 1 year ago

PP405 is a new topical treatment for hair loss, showing promise in trials but still requires finasteride for maintenance. There is skepticism about its effectiveness and safety, with concerns about needing finasteride to maintain results.

View more "hair follicle dermal condensate lineage" in community →

Experts

— no results

Try a deeper search in experts →

Clinics

— no results

Try a deeper search in clinics →