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This review highlights the possibility of safely altering hair color through innovative cosmetics by targeting key biological processes in hair follicles, using insights from mammalian pigmentation studies and drug-induced hair color changes as potential pathways.

This study found that the Dun camouflage color in horses is due to TBX3 expression, which causes uneven pigment deposition, whereas non-dun coat colors result from regulatory mutations affecting TBX3 expression.

This article discusses mouse genetic studies to explore factors influencing melanogenesis, highlighting pH and cysteine's roles, and proposes a hypothesis for human hair color diversity; it reports no new results.

This article discusses the roles of different proteins in melanogenesis and proposes a hypothesis to explain the diversity of human hair pigmentation, but it reports no new experimental results.

This review highlights the complexities of hair graying and the limitations of current models to fully replicate hair follicle pigmentary unit function, suggesting that technologies like organoids and bioprinting show promise but require further development for effective hair repigmentation interventions.