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GlossaryBone Marrow Transplantation (Hematopoietic Stem Cell Transplantation)

medical procedure replacing damaged bone marrow with healthy stem cells

Bone Marrow Transplantation (BMT), also known as Hematopoietic Stem Cell Transplantation (HSCT), is a medical procedure used to replace damaged or destroyed bone marrow with healthy bone marrow stem cells. This treatment is often used for patients with certain cancers like leukemia or lymphoma, as well as other blood or immune system disorders. The healthy stem cells can come from the patient (autologous transplant) or a donor (allogeneic transplant).

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research C3-C4 Shingles Post Hematopoietic Stem-Cell Transplantation

September 2014 in “Archives of disease in childhood”

A 12-year-old boy had severe shingles and skin damage after a stem-cell transplant.

research A Case of Red Lunulae After Hematopoietic Stem Cell Transplantation

May 2018 in “European Journal of Dermatology”

Adjusting the medication tacrolimus resolved a boy's red nail beds after a stem cell transplant.

research Permanent Diffuse Alopecia After Hematopoietic Stem Cell Transplantation in Childhood

16 citations, March 2017 in “Bone Marrow Transplantation”

Some children who had stem cell transplants developed permanent hair loss, especially when treated with a drug called busulphan.

research The Promise and Challenges of Cell Therapy for Psoriasis

15 citations, May 2021 in “British journal of dermatology/British journal of dermatology, Supplement”

Cell therapy shows promise for treating severe psoriasis but needs more research to confirm safety and effectiveness.

research Modulating the Stem Cell Niche for Tissue Regeneration

480 citations, August 2014 in “Nature Biotechnology”

Changing the environment around stem cells could help tissue repair, but it's hard to be precise and avoid side effects.

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community Painkillers May Block Minoxidil

in Research/Science 14 upvotes 4 months ago

Painkillers like Aspirin may reduce Minoxidil's effectiveness by inhibiting the enzyme PGHS-1, which is crucial for hair growth. Using NSAIDs that inhibit COX-2 or combining Minoxidil with PGF2/E2 analogues or retinoids may enhance its efficacy.