TLDR A 12-year-old boy had severe shingles and skin damage after a stem-cell transplant.
A 12-year-old boy developed rapidly spreading, severely pruritic C3-C4 shingles three months after undergoing a matched unrelated haematopoietic stem-cell transplantation (HSCT) for relapsed acute myeloid leukaemia. Despite early treatment with intravenous aciclovir, he experienced full C3-C4 dermatome skin erosion to the dermis and secondary hair loss.
5 citations,
October 2018 in “American Journal of Clinical Dermatology” Skin problems are common after stem cell transplants, and early treatment by dermatologists can improve patient outcomes.
98 citations,
March 2019 in “Frontiers in immunology” Damaging mutations in NFKB2 cause a severe and distinct form of primary immunodeficiency with early-onset and often ACTH-deficiency.
Chemotherapy can cause skin issues and hair loss, and this guide explains how to manage them.
16 citations,
March 2017 in “Bone Marrow Transplantation” Some children who had stem cell transplants developed permanent hair loss, especially when treated with a drug called busulphan.
15 citations,
May 2021 in “British journal of dermatology/British journal of dermatology, Supplement” Cell therapy shows promise for treating severe psoriasis but needs more research to confirm safety and effectiveness.
