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research The malignant capacity of skin tumours induced by expression of a mutant H-ras transgene depends on the cell type targeted

153 citations , April 1998 in “Current Biology”

This study found that benign tumors with a high risk of malignant progression primarily arise from hair follicle cells when a mutant ras gene is expressed in a specific population of epidermal cells in mice.

research Twins with psychiatric features and a nonsense HRAS variant affecting transcript processing

October 2023 in “Psychiatry research. Case reports”

In this study, researchers observed that twins with a novel de novo nonsense variant in HRAS exhibited distinctive features, including neuropsychiatric symptoms, potentially indicating a wider clinical spectrum for conditions known as RASopathies.

research Nevus Sebaceus With Novel HRAS Sequence Variant Mutation Misdiagnosed as Alopecia Areata

May 2023 in “Cutis”

In this case report, researchers diagnosed a 12-year-old girl with a nevus sebaceus of Jadassohn, characterized by a yellowish-pink plaque on the scalp and a genetic variant, following previous misdiagnosis as alopecia areata.

research Age-associated inflammation connects RAS-induced senescence to stem cell dysfunction and epidermal malignancy

56 citations , March 2015 in “Cell death and differentiation”

This study found that H-Ras activation in aged mouse skin leads to increased dysplasia and progression to in situ squamous cell carcinoma, highlighting an age-linked connection between immune changes, senescence, and cancer risk.

research Structured Oral Examinations in Internal Medicine - Case H

September 2009 in “MedEdPORTAL”

This resource outlines a structured oral examination approach for internal medicine students using a case study of systemic lupus erythematosus, highlighting its convenience and effectiveness based on student feedback.

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Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

community Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

in Research 865 upvotes 1 year ago

The treatment for androgenetic alopecia involves using finasteride and minoxidil with intense exercise and cold exposure to boost metabolism and reduce androgenic effects, potentially leading to hair regrowth. This approach may activate biological pathways for improved hair and overall health.

community Check your vitamin d3 levels!!!

158 upvotes 2 months ago

Vitamin D3 deficiency and gut health, particularly H. pylori overgrowth, can impact hair growth and overall health. Treatments like Minoxidil and finasteride may be ineffective if these issues are not addressed.

community My experience: pre-existing gyno and finasteride

3 upvotes 7 years ago

The conversation discusses experiences with finasteride for hair loss, particularly in relation to pre-existing gynecomastia. The original poster used finasteride but stopped after finding no change in gynecomastia size, and others shared similar concerns and experiences.

community Bad doctors even in the USA

171 upvotes 6 years ago

Young men are advised to delay hair transplants until after age 25, using finasteride, minoxidil, and dermarolling to manage hair loss. Concerns about unethical doctors highlight the need for careful planning.

community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

in Research 830 upvotes 2 years ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

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