January 1998 in “Proceedings of the British Society of Animal Science” This study investigated the effects of biotin deficiency and adequacy on cell proliferation and DNA synthesis in isolated mohair follicles, particularly focusing on the incorporation of [methyl-3 H]thymidine.
This study found that loss of the DNA methyltransferase Dnmt3a, but not Dnmt3b, increased carcinogen-induced squamous tumors in murine epidermis, with combined deletion leading to more aggressive and metastatic carcinomas.
January 1998 in “Proceedings of the British Society of Animal Science” This study examined the role of biotin deficiency and adequacy on cell proliferation and DNA synthesis in isolated mohair follicles.
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July 1967 in “Science” This study found that aged tritiated thymidine breaks down and incorporates into cytoplasmic macromolecules, not DNA, suggesting caution in its use.
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June 2012 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that applying topical thymidine dinucleotide (pTT) to newborn mice before UV exposure delayed and reduced melanoma development compared to untreated controls.