research Atypical Formations of Gintonin Lysophosphatidic Acids as New Materials and Their Beneficial Effects on Degenerative Diseases
New ginseng compounds may help treat degenerative diseases.
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research Cell Surface Receptor Kinase FERONIA Linked to Nutrient Sensor TORC Signaling Controls Root Hair Growth at Low Temperature Linked to Low Nitrate in Arabidopsis Thaliana
A protein called FERONIA helps control root hair growth in response to cold and low nitrogen by activating nutrient-sensing pathways in a plant called Arabidopsis.
research Targeted Inactivation of Gh/Tissue Transglutaminase II
The study investigated the role of Gh/tissue transglutaminase II (Tgm2) by creating Tgm2 knockout mice, which were viable and phenotypically normal, indicating Tgm2 was not essential for reproduction or developmental apoptosis. The absence of Tgm2 did not affect α1-adrenergic receptor signaling or thymocyte apoptosis significantly, although Tgm2−/− thymocytes were more susceptible to dexamethasone-induced cell death. Tgm2−/− fibroblasts showed reduced adherence, suggesting Tgm2's involvement in cell attachment and spreading. Cardiovascular assessments showed no significant differences between Tgm2−/− and Tgm2+/+ mice, indicating minimal involvement in cardiovascular function. The study concluded that Tgm2 played a role in stabilizing apoptotic cells and fibroblast interaction with the extracellular matrix.
research A Function for Rac1 in the Terminal Differentiation and Pigmentation of Hair
Rac1 is essential for proper hair structure and color.
research Novel TMEM173 Mutation and the Role of Disease-Modifying Alleles
A new mutation in the STING protein causes a range of symptoms and its severity may be affected by other genetic variations; treatment with a specific inhibitor showed improvement in one patient.
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1 / 1 resultscommunity Almost 20 Years on Finasteride - AMA
A user successfully halted hair loss using finasteride for 17 years and recently switched to dutasteride for stronger DHT suppression. They experienced no major side effects, maintained a full head of hair, and fathered three children without issues.