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GlossaryGlycogen Synthase Kinase-3 Inhibitor (GSK3 Inhibitor)

compound that blocks the enzyme GSK-3, affecting cell processes

A Glycogen Synthase Kinase-3 Inhibitor (GSK-3 Inhibitor) is a type of compound that blocks the activity of the enzyme glycogen synthase kinase-3 (GSK-3). This enzyme is involved in various cellular processes, including the regulation of glycogen metabolism, cell division, and signaling pathways. Inhibiting GSK-3 has potential therapeutic applications for conditions like Alzheimer's disease, diabetes, and certain types of cancer, as well as promoting hair growth in cases of alopecia.

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research Partial Proteasome Inhibitors Induce Hair Follicle Growth by Stabilizing Beta-Catenin

3 citations, January 2014 in “Stem cells”

Certain inhibitors applied to the skin can promote hair growth by maintaining a key hair growth signal.

research Identifying the Target Cells and Mechanisms of Merkel Cell Polyomavirus Infection

133 citations, June 2016 in “Cell Host & Microbe”

Human dermal fibroblasts are the main cells targeted by a virus that can cause a deadly skin cancer, and a certain inhibitor can effectively block this infection.

HaCaT-Conditioned Medium Supplemented with Small Molecule Inhibitors SB431542 and CHIR99021 and Growth Factor PDGF-AA Prevents the Dedifferentiation of Dermal Papilla Cells In Vitro

research HaCaT-Conditioned Medium Supplemented with Small Molecule Inhibitors SB431542 and CHIR99021 and Growth Factor PDGF-AA Prevents the Dedifferentiation of Dermal Papilla Cells In Vitro

7 citations, March 2021 in “Molecular Medicine Reports”

A mix of specific inhibitors and a growth factor helps keep hair growth cells from losing their properties in the lab.

research Extracellular Fraction of Adipose Tissue as an Innovative Regenerative Approach for Vitiligo Treatment

14 citations, June 2019 in “Experimental Dermatology”

Fat tissue extract may help treat vitiligo by reducing cell stress and promoting skin repair.

Mycophenolate Antagonizes IFN-γ-Induced Catagen-Like Changes via β-Catenin Activation in Human Dermal Papilla Cells and Hair Follicles

research Mycophenolate Antagonizes IFN-γ-Induced Catagen-Like Changes via β-Catenin Activation in Human Dermal Papilla Cells and Hair Follicles

11 citations, September 2014 in “International Journal of Molecular Sciences”

Mycophenolate helps reverse hair loss effects caused by IFN-γ by activating a key hair growth pathway.

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community Does melatonin dissolve in isopropyl alcohol

in Technology 8 upvotes 1 year ago

The conversation discusses making a topical melatonin solution for hair loss treatment, questioning if isopropyl alcohol can dissolve melatonin. Melatonin is soluble in lipids and alcohol, but it's unstable and should be mixed fresh regularly; it may help hair growth by affecting certain cellular signaling pathways and has anti-androgenic effects.