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research Primary Generalized Glucocorticoid Resistance or Chrousos Syndrome: Allostasis Through a Mutated Glucocorticoid Receptor

December 2016 in “Springer eBooks”

Chrousos Syndrome is caused by mutations that make the body less sensitive to glucocorticoids, leading to various symptoms and requiring high-dose treatment.

research Generalized Glucocorticoid Resistance

January 2008 in “US endocrinology”

Mutations in the glucocorticoid receptor gene cause reduced sensitivity to glucocorticoids and may lead to poor response to treatment.

A Novel Point Mutation in the Ligand-Binding Domain of the Human Glucocorticoid Receptor Causing Generalized Glucocorticoid Resistance: The Importance of the C Terminus in Conferring Transactivational Activity

research A Novel Point Mutation in the Ligand-Binding Domain of the Human Glucocorticoid Receptor Causing Generalized Glucocorticoid Resistance: The Importance of the C Terminus in Conferring Transactivational Activity

91 citations , May 2005 in “The Journal of Clinical Endocrinology & Metabolism”

A new mutation in the human glucocorticoid receptor reduces its function and causes resistance to glucocorticoids.

research The Developmental Basis of Fingerprint Pattern Formation and Variation

44 citations , February 2023 in “Cell”

Fingerprints form uniquely before birth due to specific genetic pathways and local signals.

research Differences in Reproductive Toxicology Between Alopecia Drugs: An Analysis on Adverse Events Among Female and Male Cases

24 citations , October 2016 in “Oncotarget”

Finasteride has a higher risk of reproductive side effects than minoxidil.

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community For what it's worth ("side effects" and my experience on Finasteride)

in Finasteride 6 upvotes 9 years ago

The user experienced side effects commonly attributed to Finasteride without ever taking the drug, suggesting these issues may stem from other life factors. They advise considering other potential causes before blaming Finasteride for such side effects.

community 8mg on oral finasteride. No results?

in Progress Pictures 7 upvotes 2 years ago

A user is experiencing worsening hair loss despite using 8mg of oral finasteride and is considering trying minoxidil or redoing blood work. They are concerned about thinning hair on the sides and back of their head.

community Any sources on Geranium sibiricum extract?

in Product 4 years ago

The conversation discusses the use of Minoxidil and finasteride for hair loss and explores the potential of Geranium sibiricum extract as a safer alternative. It highlights the difficulty in finding this specific extract and suggests considering other plants with similar compounds, like Indian gooseberry.

community Actor Paul Mescal, 26, has a receding hairline. I thought it was pretty cool to see a younger actor being successful, despite dealing with hair loss. He just got nominated for an Oscar.

in Chat 353 upvotes 3 years ago

Actor Paul Mescal, who has a receding hairline, and how it affects his success in the entertainment industry. People discussed how styling can help disguise hair loss, and that hair loss doesn't necessarily mean one's appearance is immediately ruined. Treatments such as Minoxidil and Finasteride were mentioned to combat hair loss.

community Tried Fin/Min..Gave me bad sides..what options do I have now?

in Treatment 6 upvotes 3 years ago

The user experienced heart palpitations from using Fin (0.1%) and Min (10%) and is seeking alternatives. Options suggested include PRP or Mesotherapy, with a recommendation to try topical Fin without Min.

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