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Chrousos Syndrome is caused by mutations that make the body less sensitive to glucocorticoids, leading to various symptoms and requiring high-dose treatment.

Mutations in the glucocorticoid receptor gene cause reduced sensitivity to glucocorticoids and may lead to poor response to treatment.

A new mutation in the human glucocorticoid receptor reduces its function and causes resistance to glucocorticoids.

The vitamin D receptor is crucial for bone health and affects various body systems, with mutations potentially leading to disease.

Estrogen therapy can reduce skin aging but has cancer risks.

Estrogens help reduce skin aging, and SERMs might offer similar benefits without the risks of hormone therapy.

Androgen receptors are key for development and health, affecting conditions like prostate cancer and male pattern baldness.

New findings explain how genetic changes, body clocks, and certain molecules affect tissue response to stress hormones.

The conclusion is that genetic changes in the glucocorticoid receptor can lead to conditions affecting stress response, immunity, and metabolism, requiring personalized treatment.

The review suggests thorough evaluation and genetic testing for proper diagnosis and treatment of Chrousos syndrome.

Certain defective glucocorticoid receptor mutants move faster inside cell nuclei and work less effectively.

Mutations in certain receptors can cause diseases and offer new treatment options.

Finasteride has a higher risk of reproductive side effects than minoxidil.

The androgen receptor is a promising target for breast cancer treatment, especially in triple-negative cases, but more research is needed for personalized therapies.

Targeting the actin cytoskeleton could improve skin healing and reduce scarring.

Mice with more Flightless I protein grew back their claws better after amputation.

The R343H mutation in the VDR gene causes vitamin D-resistant rickets with alopecia by impairing specific gene activity.

Flutamide caused damage to male rat reproductive organs and may affect fertility.

Vitamin D is important for bones, hair, blood pressure, and breast development.

Vitamin D receptor binds similarly to natural and synthetic ligands, affecting gene regulation.

Mutations in the NR3C1 gene cause a rare condition that affects hormone signaling and can lead to various symptoms, with dexamethasone as a treatment option.

Grasp protein helps maintain skin health after UVB exposure.

Ayme-Gripp Syndrome was confirmed in a woman through genetic testing, highlighting the need to consider rare genetic conditions in diagnoses.

Finasteride improves hair growth and satisfaction in men with male pattern baldness but may cause sexual side effects.

2021 saw a slow return to normalcy and increased scientific engagement despite COVID-19 challenges.

Testosterone therapy improves physical function, strength, and body composition in older men with low testosterone levels.

The man had myotonia, which caused delayed hand grip relaxation.

The sharp implanter method for hair graft placement is simpler and faster, allowing for dense packing of grafts with natural results.

New subcision technique with a bent needle and syringe improves ease, effectiveness, and comfort for treating acne scars.

Marsupial hair structure and keratin distribution are similar to placental mammals.