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    Glossary gp100

    protein in melanocytes involved in melanin production

    gp100 is a protein found in melanocytes, the cells responsible for producing the pigment melanin in the skin, hair, and eyes. It is often studied in the context of melanoma, a type of skin cancer, because it serves as a target for certain immunotherapies aimed at treating this disease.

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    Research 10 of 223

    1. The silver locus product (Silv/gp100/Pmel17) as a new tool for the analysis of melanosome transfer in human melanocyte–keratinocyte co‐culture Experimental dermatology · 2008 · 68 citations
    2. Inhibition of a signaling modality within the gp130 receptor enhances tissue regeneration and mitigates osteoarthritis Science Translational Medicine · 2023 · 1 citations
    3. Signaling modality within gp130 receptor enhances tissue regeneration bioRxiv (Cold Spring Harbor Laboratory) · 2022
    4. The Peripheral Clock Regulates Human Pigmentation 2014 · 81 citations
    5. Coming of Age of Melanogenesis-Related Proteins Archives of Pathology & Laboratory Medicine · 2002 · 37 citations
    6. Topobiology of Human Pigmentation: P-Cadherin Selectively Stimulates Hair Follicle Melanogenesis 2013 · 29 citations
    7. Beyond the Epidermal-Melanin-Unit: The Human Scalp Anagen Hair Bulb Is Home to Multiple Melanocyte Subpopulations of Variable Melanogenic Capacity 2023
    8. 558 The Bacterial Metabolite, Butyrate, Prolongs Anagen and Promotes Autophagy, Mitochondrial Activity, Melanogenesis and Antimicrobial Peptide Production in Human Scalp Hair Follicles Journal of Investigative Dermatology · 2022
    9. 518 Nutrient and stress sensing as novel physiological regulator of human hair pigmentation and greying: Role of mTORC1 activity Journal of Investigative Dermatology · 2022
    10. 650 Controlling mTORC1 activity as a novel therapeutic strategy for managing human hair growth and pigmentation 2022
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