82 citations
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February 1989 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” This study found that in men with benign prostatic hyperplasia, a 3-month treatment with a long-acting GnRH agonist significantly reduced intraprostatic DHT and 3α-diol levels by about 90% and testosterone by about 75%.
96 citations
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October 1987 in “The Journal of Clinical Endocrinology & Metabolism” This study found that long-term GnRH agonist administration in premenopausal women with polycystic ovarian disease resulted in persistent suppression of ovarian steroid secretion, while adrenal steroid levels remained unchanged.
May 2022 in “The Journal of Clinical Pharmacology” This study suggests that metformin has a stronger impact on gonadotroph hormone levels in men with early-onset androgenic alopecia compared to those with normal hair growth.
4 citations
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September 2018 in “Journal of Drug Delivery and Therapeutics” This article discusses the pathophysiology and treatment of polycystic ovary syndrome and reports no new results, emphasizing the higher risk of metabolic and cardiovascular issues for affected women.
28 citations
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January 2017 in “Obstetrician & gynaecologist/The obstetrician & gynaecologist” This article discusses the complexities of diagnosing and managing polycystic ovary syndrome, highlighting the challenges related to fertility treatment criteria, insulin resistance, and long-term health implications, but reports no new clinical findings.