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    GlossaryGlycosaminoglycans

    long sugar chains in connective tissues aiding structure and signaling

    Glycosaminoglycans (GAGs) are long, unbranched polysaccharides composed of repeating disaccharide units that play a crucial role in the extracellular matrix of connective tissues. They help maintain structural integrity, provide lubrication in joints, and are involved in cell signaling processes.

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      community Minoxidil Sulfate makes everyone a responder

      in Research/Science  261 upvotes 10 months ago
      Minoxidil sulfate is more effective than regular minoxidil, especially for those with low sulfotransferase levels or scalp sensitivity, but it is unstable unless delivered in a liposomal format. Combining minoxidil with tretinoin can enhance effectiveness, and stopping minoxidil use can lead to rapid hair loss.

      community DLQ01: A Better "Minoxidil" PGF2a synthetic analogue.

      in Research/Science  3 upvotes 6 months ago
      DLQ01, a prostaglandin F2α analog, shows promise for hair growth by directly stimulating PGE2/PGF receptors without needing conversion, and can be combined with minoxidil and retinoids like tretinoin for enhanced effectiveness. Minoxidil's efficacy may be reduced by COX-1 inhibitors, but using prostaglandin analogs like Latanoprost or Bimatoprost can help maintain its effectiveness.