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    GlossaryGlycosaminoglycans

    long sugar chains in connective tissues aiding structure and signaling

    Glycosaminoglycans (GAGs) are long, unbranched polysaccharides composed of repeating disaccharide units that play a crucial role in the extracellular matrix of connective tissues. They help maintain structural integrity, provide lubrication in joints, and are involved in cell signaling processes.

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      community Minoxidil Sulfate makes everyone a responder

      in Research/Science  258 upvotes 4 months ago
      Minoxidil sulfate is more effective than regular minoxidil, especially for those with low sulfotransferase levels or scalp sensitivity, but it is unstable unless delivered in a liposomal format. Combining minoxidil with tretinoin can enhance effectiveness, and stopping minoxidil use can lead to rapid hair loss.

      community DLQ01: A Better "Minoxidil" PGF2a synthetic analogue.

      in Research/Science  3 upvotes 1 month ago
      DLQ01, a prostaglandin F2α analog, shows promise for hair growth by directly stimulating PGE2/PGF receptors without needing conversion, and can be combined with minoxidil and retinoids like tretinoin for enhanced effectiveness. Minoxidil's efficacy may be reduced by COX-1 inhibitors, but using prostaglandin analogs like Latanoprost or Bimatoprost can help maintain its effectiveness.