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Did you mean Glycogen Synthase Kinase 3?

Glossary Glycogen Synthase Kinase 3

enzyme involved in regulating cell functions and signaling pathways

Glycogen Synthase Kinase 3 (GSK-3) is an enzyme that plays a crucial role in various cellular processes, including the regulation of glycogen synthesis, cell division, and cell survival. It is involved in multiple signaling pathways and can influence conditions like diabetes, Alzheimer's disease, and even hair growth by affecting cellular functions and gene expression.

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Beta-Catenin Inactivation Is a Prerequisite for Chick Retina Regeneration

research β-Catenin Inactivation Is a Pre-Requisite for Chick Retina Regeneration

29 citations , July 2014 in “PLoS ONE”

This study suggests that inactivation of β-catenin is necessary for chick retina regeneration, as it allows cells to enter the cell cycle during injury and promotes regeneration without needing FGF2.

research CD133-positive dermal papilla-derived Wnt ligands regulate postnatal hair growth

15 citations , July 2016 in “Biochemical Journal”

This study found that Wnt ligands from CD133-positive dermal papilla cells are essential for maintaining hair growth by supporting cell signaling between different hair follicle structures.

research The Secretome of Irradiated Peripheral Mononuclear Cells Attenuates Hypertrophic Skin Scarring

1 citations , March 2023 in “Pharmaceutics”

This study found that PBMCsec has anti-fibrotic effects on mouse and human skin scars by regulating pro-fibrotic gene expression and inhibiting myofibroblast differentiation and elastic fiber breakdown.

research Manifestation of pityriasis amiantacea following initiation of minoxidil

1 citations , April 2022 in “JAAD case reports”

In this case report, researchers observed that a 47-year-old woman developed pityriasis amiantacea after using topical minoxidil, suggesting a potential new etiology for this scalp condition.

research Role and Mechanisms of Phytochemicals in Hair Growth and Health

2 citations , January 2023 in “Pharmaceuticals”

This review discusses factors affecting hair health, types of alopecia, and the potential of phytochemicals in managing hair loss but reports no new clinical results; it highlights the need for further studies.

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community Better Than Minoxidil? Topical Sodium Valproate

50 upvotes 1 year ago

Topical sodium valproate may promote hair growth by inhibiting GSK3β, allowing beta-catenin to proliferate, but it has potential side effects and requires more research. The conversation also mentions skepticism about a product called Vdphlo1, which includes sodium valproate and other ingredients.

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Hair Loss Specialist
Monica Calcagni
Milan, Italy

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Monica Calcagni