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Inhibition of the Mitochondrial Pyruvate Carrier Promotes ATF4-Dependent Stress Responsive Metabolic Rewiring and Cell Cycle Arrest in the Human Hair Follicle

research Inhibition of the Mitochondrial Pyruvate Carrier Promotes ATF4-Dependent Stress Responsive Metabolic Rewiring and Cell Cycle Arrest in the Human Hair Follicle

April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology”

Blocking a key energy pathway in human hair follicles can trigger stress responses that stop cell growth.

A Glutathione-Dependent Control of the Indole Butyric Acid Pathway Supports Arabidopsis Root System Adaptation to Phosphate Deprivation

research A Glutathione-Dependent Control of the Indole Butyric Acid Pathway Supports Arabidopsis Root System Adaptation to Phosphate Deprivation

27 citations, April 2020 in “Journal of Experimental Botany”

Glutathione helps Arabidopsis roots adapt to low phosphate by regulating a specific growth pathway.

research Remodeling of Root Growth Under Combined Arsenic and Hypoxia Stress Is Linked to Nutrient Deprivation

30 citations, October 2020 in “Frontiers in Plant Science”

Combined arsenic and low oxygen stress alters root growth to help plants absorb nutrients.

research Activation of the Integrated Stress Response in Human Hair Follicles

June 2024 in “PLoS ONE”

Blocking the Mitochondrial Pyruvate Carrier causes stress in hair follicles, which can be reduced by an ISR inhibitor.

The Mechanisms and Management of Age-Related Oxidative Stress in Male Hypogonadism Associated with Non-Communicable Chronic Disease

research The Mechanisms and Management of Age-Related Oxidative Stress in Male Hypogonadism Associated with Non-Communicable Chronic Disease

16 citations, November 2021 in “Antioxidants”

Managing oxidative stress might help treat low testosterone and related chronic diseases in aging men.

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community I will have it cured by morning

in Research/Science 370 upvotes 1 year ago

Researching the cause of hair loss and treating it by preventing DHT in the scalp with medication such as finasteride or dutasteride, estrogen, minoxidil, dermarolling, and possible topical antiandrogens.

community Obviously, all of us who are serious take antiandrogens and growth stimulants - what else are you doing lifestyle wise, dietary wise, and regiment wise to maximize your results?

in Treatment 21 upvotes 4 months ago

The user follows a hair loss treatment routine including Propecia, oral minoxidil, ketoconazole, and plans to switch to dutasteride. They also focus on lifestyle changes, dietary supplements, and are considering laser therapy.

community One year progress on fin and min

in Progress Pictures 176 upvotes 5 months ago

A user shared one-year progress using finasteride and minoxidil for hair loss at age 42. Suggestions included adding dermastamping, microneedling, and considering a hair transplant for further improvement.

community Anything you use without scientific backing, just trusting your gut?

in Research/Science 13 upvotes 1 year ago

The conversation discusses using peppermint oil for hair loss, with one user applying it undiluted to the scalp and another combining it with finasteride and microneedling. Some believe in its effectiveness despite limited scientific evidence, and also mention rosemary oil as potentially beneficial.

community Nice & pure PRP, 3 ml of this is going to the scalp.

in Research/Science 32 upvotes 2 years ago

The use of PRP to treat hair loss and its potential effectiveness when combined with 5 alpha reductase blockers such as Minoxidil or Finasteride.

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