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Androstanediol Glucuronide

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research Plasma Levels of C19 Steroid Glucuronides in Pre-Menopausal Women with Non-Classical Congenital Adrenal Hyperplasia

7 citations, April 1992 in “Journal of steroid biochemistry and molecular biology/The Journal of steroid biochemistry and molecular biology”

Women with non-classical congenital adrenal hyperplasia have higher levels of certain steroids, which can be reduced by treatment.

research High-Resolution Mass Spectrometric Investigation of the Phase I and II Metabolites of Finasteride in Pig Plasma, Urine, and Bile

2 citations, December 2013 in “Xenobiotica”

Finasteride metabolites found in pigs match human studies, making pigs a valid model for human drug research.

research Evaluation of Glucuronide Metabolite Stability in Dried Blood Spots

26 citations, December 2012 in “Bioanalysis”

Dried blood spots can be as stable as frozen liquid samples for storing certain metabolites.

research Is Dehydroepiandrosterone a Hormone?

403 citations, November 2005 in “Journal of Endocrinology”

Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.

research Anthracycline Analogs: The Past, Present, And Future

168 citations, December 1986 in “Cancer Chemotherapy and Pharmacology”

Epirubicin is as effective as doxorubicin for cancer treatment with less heart damage, but doesn't work on doxorubicin-resistant cancers.

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community Bile Acid-Mediated DHT Dysregulation Hypothesis

in Research/Science 13 upvotes 2 weeks ago

Elevated bile acids can inhibit the enzyme AKR1C2, leading to increased DHT levels, which may accelerate hair loss in those predisposed to androgenetic alopecia. Treatments mentioned include topical minoxidil and finasteride.

community Why isn't anybody on topical bicalutamide?

in Research/Science 2 upvotes 5 months ago

Topical bicalutamide is discussed as a potential hair loss treatment. Other treatments mentioned include Minoxidil, finasteride, and RU58841.

community Insane dutasteride shed 4 months after switching.

in Finasteride/Dutasteride 115 upvotes 1 year ago

The post and conversation are about a user's experience with hair loss treatments, specifically switching from finasteride to dutasteride. The user experienced significant hair shedding after the switch, with others suggesting patience, noting similar experiences, or questioning the user's decision and medical consultation.

community Oral Minoxidil and Grapefruit Juice

in Research/Science 96 upvotes 1 year ago

The conversation is about the potential dangers of taking oral minoxidil and grapefruit juice together. Some users express concern about dangerous drug interactions, while others argue that grapefruit juice may inhibit the metabolism of finasteride. The conclusion is that grapefruit juice may make finasteride less effective, but it won't affect minoxidil.

community blood DHT levels shot up after doubling dutasteride dosage

in Finasteride/Dutasteride 20 upvotes 6 months ago

A user increased their dutasteride dosage from 0.5mg to 1mg daily, resulting in a rise in DHT levels from 148 pg/mL to 281 pg/mL, and is considering switching back to finasteride due to continued hair loss. Replies suggest retesting and emphasize the importance of bloodwork before starting treatments.

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