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research Recent Advances in the Molecular Mechanisms Causing Primary Generalized Glucocorticoid Resistance

15 citations , April 2016 in “Hormones”

Mutations in the NR3C1 gene cause a rare condition that affects hormone signaling and can lead to various symptoms, with dexamethasone as a treatment option.

research Restricted Effects of Androgens on Glucocorticoid Signaling in the Mouse Prefrontal Cortex and Midbrain

3 citations , January 2024 in “Frontiers in Endocrinology”

Androgens can affect glucocorticoid signaling in specific mouse brain areas.

research Faculty Opinions Recommendation of Targeted Skin Overexpression of the Mineralocorticoid Receptor in Mice Causes Epidermal Atrophy, Premature Skin Barrier Formation, Eye Abnormalities, and Alopecia

August 2007 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature”

Overexpression of a specific receptor in mice skin causes skin thinning, early skin barrier formation, eye issues, and hair loss.

research Novel Insights Into the Molecular Mechanisms Underlying Generalized Glucocorticoid Resistance and Hypersensitivity Syndromes

15 citations , April 2017 in “Hormones”

Genetic defects in the glucocorticoid receptor gene can cause conditions with abnormal sensitivity to stress hormones, and other factors may also affect this sensitivity.

research Glucocorticoid Receptor Antagonism Improves Glucose Metabolism in a Mouse Model of Polycystic Ovary Syndrome

December 2023 in “Journal of the Endocrine Society”

Blocking glucocorticoid receptors improves glucose metabolism in a PCOS mouse model.

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community New and Interesting HairLoss Studies/Papers/Reviews

in Treatment 42 upvotes 6 years ago

Hair loss treatments discussed include Dutasteride with Ketoconazole, tissue engineering strategies, and androgenetic alopecia therapies. Massage doubles follicular retention, improving treatment effectiveness.

community NootBro Recommendations… How Do We Feel

in Research/Science 9 upvotes 1 year ago

The conversation is about hair loss treatments, specifically a stack including topical Ashwagandha, Copper Peptide, Gotu Kola, Ketoconazole, and PDA. One user found Topical and Sub-Q GHK-CU effective.

community Pyrilutamide is working but not strong enough, how long should i wait for noticeable results?

in Update 3 upvotes 2 years ago

User discusses Pyrilutamide's effectiveness for hair loss, needing more time for results. Others suggest waiting 6-12 months and ask about side effects.

community We Need A Solution For The Inflammatory Response related To AGA

in Research/Science 16 upvotes 1 year ago

The conversation is about finding a solution for scalp inflammation related to AGA, with the user expressing frustration that Minoxidil and Finasteride do not address inflammation. The user has researched glucocorticoids and topical NSAIDs for reducing inflammation and seeks advice from specialists.

community AA and Hirsutism but T levels are normal

in Female 8 upvotes 5 years ago

27-year-old female experiences aggressive hair thinning and hirsutism despite normal testosterone levels. Spironolactone and 2% minoxidil were ineffective; high DHEA sulfate levels may be the cause.

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