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Mutations in the NR3C1 gene cause a rare condition that affects hormone signaling and can lead to various symptoms, with dexamethasone as a treatment option.

Genetic defects in the glucocorticoid receptor gene can cause conditions with abnormal sensitivity to stress hormones, and other factors may also affect this sensitivity.

Blocking glucocorticoid receptors improves glucose metabolism in a PCOS mouse model.

Overexpression of a specific receptor in mice skin causes skin thinning, early skin barrier formation, eye issues, and hair loss.

The conclusion is that genetic changes in the glucocorticoid receptor can lead to conditions affecting stress response, immunity, and metabolism, requiring personalized treatment.

Chrousos Syndrome is caused by mutations that make the body less sensitive to glucocorticoids, leading to various symptoms and requiring high-dose treatment.

New findings explain how genetic changes, body clocks, and certain molecules affect tissue response to stress hormones.

Mutations in the glucocorticoid receptor gene cause reduced sensitivity to glucocorticoids and may lead to poor response to treatment.

The review suggests thorough evaluation and genetic testing for proper diagnosis and treatment of Chrousos syndrome.

Mice that can regenerate tissue have cells that pause in the cell cycle, which is important for healing, similar to axolotls.

Common Black hair care products may affect hormone levels and potentially impact health, especially in reproductive and metabolic areas.

Blackcurrant extract may help reduce hair loss by promoting stem cell activity in hair follicles.

Jagged-1 in skin Tregs is crucial for timely wound healing by recruiting specific immune cells.

A protein called EGFR protects hair follicle stem cells, and when it's disrupted, hair follicles can be damaged, but blocking certain pathways can restore hair growth.

DHEA affects multiple receptors and may help with metabolic issues, but its safety and effectiveness in humans are unclear.

Glucocorticoids affect dogs' skin reactions to histamine, which vary by time of day.

Hormones affect skin aging, and treatments targeting hormonal balance may improve skin health.

Hirsutism can be caused by various conditions besides PCOS, and it's important to treat the underlying issue and manage symptoms with medication and cosmetic approaches.

Clascoterone is safe for the heart, even at high doses.

Shift nurses show altered body temperature and stress hormone levels, suggesting their body clocks adjust to irregular schedules.

Intense exercise at night can delay the body's internal clock gene expression by 2 to 4 hours.

Skin health and diseases are closely linked to metabolic processes.

Skin stem cells remember past inflammation, helping them respond better to future injuries and possibly aiding in treating skin issues.

Lymphatic vessels are important for skin repair and could affect skin disease treatments.

Hair follicle stem cells help skin heal and grow during stretching.

Different immune responses cause hair loss in scalp diseases, with unique patterns in scalp psoriasis possibly protecting against hair loss.

BMAL1 and Period1 genes can influence human hair growth.

T-regulatory cells are important for skin health and can affect hair growth and reduce skin inflammation.

The SOSTDC1 gene is crucial for determining sheep wool type.

Delta-opioid receptors affect skin cell circadian rhythms, possibly impacting wound healing and cancer.