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signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss
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research Global Burden of Skin Disease as Reflected in Cochrane Database of Systematic Reviews
The representation of skin conditions in medical reviews partly matches their real-world impact.
research Global Burden of Alopecia Areata and Associated Diseases: A Trend Analysis From 1990 to 2021
Alopecia areata cases have increased globally, affecting mostly women aged 30-34, with links to other health issues.
research Disease Burden, Clinical Management, and Unmet Treatment Need of Patients With Moderate to Severe Alopecia Areata: Consensus Statements, Insights, and Practices From CERTAAE Delphi Panel
Alopecia Areata significantly lowers quality of life and current treatments are inadequate, highlighting a need for better therapies and standardized treatment protocols.
research Epidemiology and Burden of Alopecia Areata: A Systematic Review
Alopecia areata is a common autoimmune disease affecting about 2% of people, causing significant disability and often associated with mental health issues and other autoimmune conditions.
research Patient Prioritisation of Impact Items to Develop the Patient-Reported Impact of Dermatological Diseases (PRIDD) Measure: European Delphi Data
Patients with skin diseases rated psychological effects as most impactful, needing a treatment approach that addresses both mind and body.
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community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied
Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.
community Efficacy and Tolerability of N-Acetyl-Cysteine for Treatment of The Early-onset Androgenetic Alopecia in Men
N-Acetyl-Cysteine (NAC) was found to improve hair parameters in men with early-onset androgenetic alopecia, showing increased terminal hair count and decreased vellus hair count, with good tolerability. NAC, used alone or with minoxidil, may help due to its antioxidant properties, though its effectiveness can vary among individuals.
community Effect of dutasteride 0.5 mg/d in men who don't respond to finasteride (study)
Dutasteride improved hair density and thickness in men who didn't respond to finasteride, with some experiencing transient sexual dysfunction. Users discussed switching from finasteride to dutasteride, noting initial shedding but eventual hair improvement.
community Can we trust indian medication?
The conversation discusses the trustworthiness of Indian medications for hair loss, with some users mentioning they have purchased Minoxidil, finasteride, and RU58841 from India. Concerns include dosage and ingredient variations, but no harmful effects are noted.
community If ancient hunter gatherer women had just selected for men with hair we wouldn't be in this mess
Hair loss is humorously blamed on ancient selection preferences, with discussions on genetics and societal norms. Treatments like finasteride are mentioned as modern solutions.