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research Global Burden of Skin Disease as Reflected inCochrane Database of Systematic Reviews

70 citations , May 2014 in “JAMA Dermatology”

This study found that systematic review and protocol topics in the Cochrane Database for skin conditions are partly aligned with disease burden metrics, with some conditions overrepresented and others underrepresented compared to their disability-adjusted life years.

research Global Burden of Alopecia Areata and Associated Diseases: A Trend Analysis From 1990 to 2021.

February 2025 in “PubMed”

This study found that although the global incidence of alopecia areata has risen since 1990, age-standardized rates have slightly decreased, with significant comorbidity associations varying by region.

research Burden of immune-related skin diseases worldwide, 1991–2021: insights and prediction from the Global Burden of Disease Study

2 citations , November 2025 in “Frontiers in Immunology”

In this study, researchers highlighted the high global prevalence of immune-related skin diseases like dermatitis and psoriasis, noting that females are disproportionately affected, emphasizing the need for tailored public health strategies based on sex and region.

research Global, Regional, and National Burden of Alopecia Areata and its Associated Comorbidities, 1990–2021, and Projections to 2050: An Analysis of the Global Burden of Disease Study 2021

1 citations , August 2025 in “Acta Dermato Venereologica”

This study found that from 1990 to 2021, the global age-standardized prevalence, incidence, and years lived with disability of alopecia areata decreased, with females being more affected, and highlighted the importance of addressing psychological disorders in children with alopecia areata under age 14.

research Global, regional and national burden of alopecia areata from 1990 to 2021: a systematic analysis of the global burden of disease study 2021, with predictions to 2040

February 2026 in “Archives of Dermatological Research”

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community Efficacy and Tolerability of N-Acetyl-Cysteine for Treatment of The Early-onset Androgenetic Alopecia in Men

26 upvotes 4 years ago

N-Acetyl-Cysteine (NAC) was found to improve hair parameters in men with early-onset androgenetic alopecia, showing increased terminal hair count and decreased vellus hair count, with good tolerability. NAC, used alone or with minoxidil, may help due to its antioxidant properties, though its effectiveness can vary among individuals.

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