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A Guide for Building Biological Pathways with Two Case Studies: Hair and Breast Development

research A guide for building biological pathways along with two case studies: hair and breast development

5 citations , October 2014 in “Methods”

This article describes how PESCADOR software assists in creating detailed biological pathway charts from PubMed abstracts, focusing on hair and breast development case studies without providing new clinical results.

research Genomics

3 citations , June 2004 in “Critical Care Nurse”

This article reviews the importance of genomics in critical care nursing and highlights the need for nurses to understand genetic concepts and advancements to improve patient care, without providing new results.

research Study design for the Stanford Dermatology Personal Genomics Project

May 2014 in “Journal of The American Academy of Dermatology”

The project aimed to understand how genetic test results affect patients' actions and feelings in dermatology.

research The genetics of alopecia areata: What's new and how will it help our patients?

43 citations , May 2011 in “Dermatologic therapy”

This study identified at least eight genetic regions associated with alopecia areata, which may lead to the development of new targeted therapies based on these findings.

research MendelVar: gene prioritization at GWAS loci using phenotypic enrichment of Mendelian disease genes

2 citations , April 2020 in “bioRxiv (Cold Spring Harbor Laboratory)”

This article discusses the MendelVar webserver, which integrates Mendelian disease data with GWAS findings to prioritize candidate genes for complex traits and reports no new experimental results.

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community Genomic Sequencing for Hair Loss

in Research/Science 156 upvotes 5 months ago

Hair loss treatments like Minoxidil, finasteride, and potential mRNA therapies are discussed. There is skepticism about targeting specific genes due to the complex genetic nature of hair loss.

community Fagron TrichoTest says Finasteride won't help

10 upvotes 2 years ago

The user received a Fagron TrichoTest indicating that Finasteride, Dutasteride, and Minoxidil are not effective for them, recommending Latanoprost, Spironolactone, IGrantine-F1 TM, and Trichoxidil instead. Other users expressed skepticism about the test's validity and suggested sticking with proven treatments like Finasteride and Dutasteride.

community How is it possible for someone to be a non responder to ORAL minoxidil?

in Minoxidil 66 upvotes 2 years ago

Some individuals do not respond to oral minoxidil for hair loss, despite it generally working by improving blood flow to hair follicles. Factors like metabolism, drug interactions, and individual variations in the drug's activation may influence its effectiveness.

community We already know how to permanently fix hair loss. The science is done. The only thing missing is the funding to run one experiment.

in Technology 613 upvotes 4 months ago

A permanent hair loss solution could involve reprogramming hair follicles to resist DHT using mRNA and siRNA. However, high costs, safety concerns, and the pharmaceutical industry's preference for ongoing treatments over one-time cures are major obstacles, with finasteride and minoxidil remaining standard treatments.

community if Post Finasteride Syndrome is real. Why is it only the negative effects and not positive have log term effect?

in Finasteride/Dutasteride 63 upvotes 4 months ago

Finasteride is used for hair loss, with mixed reports of no side effects and claims of long-term negative effects known as Post Finasteride Syndrome (PFS). The conversation debates the existence and causes of PFS, with differing opinions on whether it is psychological or real.

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