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GlossaryGene Editing

technique to precisely alter an organism's DNA sequence

Gene editing, also known as genome editing, is a technique that allows scientists to alter an organism's DNA with high precision. This process involves adding, removing, or modifying specific genetic material at particular locations in the genome, often using tools like CRISPR-Cas9. It holds potential for treating genetic disorders, improving crop resilience, and even addressing hair loss conditions like alopecia by targeting and correcting the underlying genetic causes.

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research CRISPR/Cas9-Based Targeted Genome Editing for Correction of Recessive Dystrophic Epidermolysis Bullosa Using iPS Cells

1 citations , September 2019 in “Journal of Investigative Dermatology”

The research showed that CRISPR/Cas9 can fix mutations causing a skin disease in stem cells, which then improved skin grafts in mice, but more work on safety and efficiency is needed.

research Effect of Gamma-Ray Exposure on the Genome-Editing Efficiency of Improved Genome-Editing via Oviductal Nucleic Acids Delivery (i-GONAD)

January 2025 in “EXPERIMENTAL ANIMALS”

Gamma-ray exposure improves genome editing efficiency in mice using the i-GONAD method.

research Development of an Intrinsic Skin Sensor for Blood Glucose Level with CRISPR-Mediated Genome Editing in Epidermal Stem Cells

April 2017 in “Journal of Investigative Dermatology”

Researchers created a skin graft that senses blood glucose and could treat diabetes using CRISPR-edited stem cells.

Recent Advances in Genome-Editing Technology with CRISPR/Cas9 Variants and Stimuli-Responsive Targeting Approaches within Tumor Cells: A Future Perspective of Cancer Management

research Recent Advances in Genome-Editing Technology with CRISPR/Cas9 Variants and Stimuli-Responsive Targeting Approaches within Tumor Cells: A Future Perspective of Cancer Management

1 citations , April 2023 in “International Journal of Molecular Sciences”

New CRISPR/Cas9 variants and nanotechnology-based delivery methods are improving cancer treatment, but choosing the best variant and overcoming certain limitations remain challenges.

Efficient Genome Editing Using CRISPR/Cas9 Ribonucleoprotein Approach in iPS Cells for Recessive Dystrophic Epidermolysis Bullosa

research Efficient Genome Editing Using CRISPR/Cas9 Ribonucleoprotein Approach in iPS Cells for Recessive Dystrophic Epidermolysis Bullosa

April 2019 in “Journal of Investigative Dermatology”

Researchers fixed gene mutations causing a skin disease in stem cells, which then improved skin grafts in mice.

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community How do you think Shah Rukh Khan maintains his full head of hair at 60?

in Chat 453 upvotes 3 months ago

Shah Rukh Khan's hair at 60 is attributed to genetics, with speculation about using finasteride, minoxidil, or hair transplants. Some believe it's due to good genes, while others think he might use treatments or have had hair procedures.

community I believe CRISPR-on & CRISPR-off is an ultimate CURE for baldness, unlike Hair Cloning or hair loss treatments.

in Research/Science 23 upvotes 4 years ago

The conversation discusses CRISPR-on & CRISPR-off as a potential cure for baldness, contrasting it with hair cloning and other treatments like Minoxidil, finasteride, and RU58841. It also mentions the potential of mRNA for gene expression control and the prioritization of gene editing for severe genetic conditions.

community The pessimism about the Crisp Cas 9 is excessive

in Chat 12 upvotes 5 months ago

CRISPR Cas9 could potentially treat baldness by targeting specific genes in hair follicles without affecting other body functions. There is optimism about its future use, despite ethical concerns and the current reliance on treatments like minoxidil and finasteride.

community CRISPR Is Curing People Right Now. Genetic Hair Loss is Next?

in Technology 110 upvotes 1 year ago

CRISPR shows promise for treating hair loss by targeting specific genes. Current treatments include Minoxidil and finasteride, but CRISPR could offer a more precise solution, though it is still expensive and in early stages.

community How is there zero improvement with finding the cure?

in Research/Science 245 upvotes 1 month ago

Hair loss treatments have not advanced since 2018, with finasteride, minoxidil, and RU58841 still being the main options. A permanent cure is unlikely due to the profitability of ongoing treatments.

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