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    Did you mean Hair Shaft Disorders?
    GlossaryHair Shaft Disorders

    conditions affecting hair structure, causing brittleness and breakage

    Hair Shaft Disorders are conditions that affect the structure and integrity of the hair shaft, leading to issues like brittleness, breakage, and abnormal hair texture. These disorders can be genetic or acquired and often result from defects in the proteins that make up the hair, such as keratin, or from external factors like excessive heat or chemical treatments.

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      learn HMI-115

      much-hyped research compound targeting prolactin receptor in scalp

      learn SCUBE3

      a signaling molecule from dermal papilla cells being actively researched
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      learn Dutasteride

      Heavy duty finasteride that comes with higher risks, but scalp injections seem safe and are gaining popularity

    Research

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      The Genetics of Hair Shaft Disorders

      research The Genetics of Hair Shaft Disorders

      59 citations, June 2008 in “Journal of The American Academy of Dermatology”
      The article explains the genetic causes and symptoms of various hair disorders and highlights the need for more research to find treatments.
      Genetic Hair Disorders: A Review

      research Genetic Hair Disorders: A Review

      26 citations, July 2019 in “Dermatology and Therapy”
      The conclusion is that genetic testing is important for diagnosing and treating various genetic hair disorders.
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      Hair Shaft Disorders: A Rare Case Series

      research Hair Shaft Disorders: A Rare Case Series

      February 2022 in “International journal of research in dermatology”
      The document concludes that proper diagnosis and treatment of hair shaft disorders require understanding their unique causes and avoiding hair-damaging practices.

    Community Join

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      community How does hair loss and recovery work?

      in Chat  12 upvotes 4 months ago
      Hair loss varies due to genetic sensitivity to DHT and other factors. Treatments discussed include finasteride, minoxidil, RU58841, and microneedling.
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      community Wtf have we been doing for the last 30 years

      in Treatment  548 upvotes 1 month ago
      Hair loss treatments like finasteride, minoxidil, and dutasteride work but have side effects. A permanent cure is still not available due to the complexity of hair loss and limited investment.
      If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      in Research  828 upvotes 5 months ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community Why we need to be more open as men

      in Chat 1 year ago
      The emotional difficulty of hair loss for men and how society can be more understanding; various methods to address hair loss, such as finasteride, minoxidil, and RU58841; and why it is important to normalize caring about one's looks.