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Glossary Gene Expression

process where genetic information directs protein or RNA synthesis

Gene expression is the process by which information from a gene is used to synthesize functional gene products, such as proteins or RNA. This process involves two main stages: transcription, where the DNA sequence of a gene is copied into mRNA, and translation, where the mRNA is used as a template to build proteins. Gene expression is tightly regulated to ensure that the right genes are expressed at the right times and in the right amounts, which is crucial for normal development, cellular function, and response to environmental changes.

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Research

5 / 1000+ results

research 1358 PRC1 fine-tunes gene repression and activation to safeguard skin epithelium development and stem cell specification

1 citations , April 2018 in “Journal of Investigative Dermatology”

This study found that Polycomb repressive complex 1 is crucial for skin development and stem cell specification, influencing gene activity beyond its known repressor functions.

research Gene Expression of Mouse S100A3, a Cysteine-Rich Calcium-Binding Protein, in Developing Hair Follicle

40 citations , November 1998 in “The journal of investigative dermatology/Journal of investigative dermatology”

This study found that the S100A3 gene is exclusively expressed in hair follicle cells differentiating into hair shaft components in mice, suggesting its important role in hair formation.

research Mechanism of Apoptotic Regulation of Follicular Regression

2 citations , June 2001 in “American Journal of Pathology”

This article explores the complexity and significance of the hair follicle, emphasizing new insights into its biological roles and the involvement of p53 in follicular regression.

research Post-transcriptional Regulation of Keratinocyte Progenitor Cell Expansion, Differentiation and Hair Follicle Regression by miR-22

52 citations , May 2015 in “PLOS Genetics”

This study found that the microRNA miR-22 is a key regulator of the hair cycle, influencing hair loss by promoting the transition from growth to rest phases and repressing keratinocyte differentiation.

research The Role of the Hairless (hr) Gene in the. Regulation of Hair Follicle Catagen Transformation

166 citations , July 1999 in “American Journal Of Pathology”

This study found that the loss of a functional hr gene in mice leads to premature and abnormal hair follicle regression, disrupting normal hair cycling and architecture.

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Community Join

5 / 345 results

community 21M Concerned About Temple Recession: Minoxidil/Finasteride Worth It?

in General 203 upvotes 9 months ago

A 21-year-old is experiencing hair loss and is considering using Minoxidil and Finasteride, but is concerned about lifelong dependency and seeks advice on permanent solutions. They are advised to act quickly, consider additional treatments like Dutasteride, and get blood tests to rule out other causes.

community Hair Loss Causes Depression. Not Finasteride.

187 upvotes 7 months ago

Finasteride and Dutasteride do not cause depression or mood disorders; hair loss itself may be a more significant factor. Some users experience side effects from Finasteride, but it is generally well-tolerated.

community Dutasteride users- when and how did it go for you?

in Finasteride/Dutasteride 58 upvotes 9 months ago

Dutasteride can stabilize or improve hair loss but may cause side effects like depression and anxiety. Users often switch from finasteride to dutasteride for stronger results, with varied experiences in shedding and regrowth.

community 1 year vs 2 years on 1mg Finasteride [29M]

in Progress Pictures 16 upvotes 8 months ago

The user has been on 1mg finasteride daily for two years, experiencing initial shedding and some hairline recession, with limited regrowth. Suggestions include using oral minoxidil, switching to dutasteride, or considering a hair transplant for better results.

community I didn’t realize how much hair loss messes with your head until it happened

in Chat 272 upvotes 7 months ago

Hair loss affects mental health and self-esteem, causing anxiety and depression. Treatments like finasteride, minoxidil, and hair transplants help some, but others continue to struggle.

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Learn

5 / 800 results

learn Valproic acid

an anticonvulsant repurposed for hair loss via histone inhibition

learn Epidermal Growth Factor

learn Stem Cell Factor

learn Beta Polypeptide

learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

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Clinics

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Hair Loss Treatments
Gene Lee Skin ClinicSan Diego, CA · US

Experts

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