learn Tretinoin
the gold standard retinoid in dermatology that's also helpful for hair regrowth alongside Minoxidil
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5 / 9 resultslearn Valproic acid
an anticonvulsant repurposed for hair loss via histone inhibition
learn Epidermal Growth Factor
learn Stem Cell Factor
learn sh-Polypeptide-7
Research
5 / 1000+ resultsresearch The Organization of the Keratin I and II Gene Clusters in Placental Mammals and Marsupials Show a Striking Similarity
Keratin gene clusters in humans and marsupials are similarly organized.
research Genomewide Analysis of Copy Number Variants in Alopecia Areata in a Central European Cohort Reveals Association with MCHR2
MCHR2 gene duplications may be linked to alopecia areata.
research Increased Rate of Hair Keratin Gene Loss in the Cetacean Lineage
Cetaceans lost hair genes to adapt to water.
research Recent Advances in Neuropeptide-Related Omics and Gene Editing: Spotlight on NPY and Somatostatin and Their Roles in Growth and Food Intake of Fish
New tools show that in fish, NPY increases feeding and somatostatin decreases it.
research Evolution of Trichocyte Keratins
Hair keratins evolved from ancient proteins, diversifying through gene changes, crucial for forming claws and later hair in mammals.
Community Join
5 / 453 resultscommunity Starting an experiment to test DHT levels with Fin and Creatine.
The user experimented with finasteride to reduce hair loss and plans to test if creatine affects DHT levels while on finasteride. Initial results showed low DHT levels, indicating finasteride's effectiveness, with further tests planned for creatine's impact.
community 22 years since the last major development
The conversation discusses the lack of significant advancements in hair loss treatments since the introduction of finasteride 22 years ago, with many expressing frustration over the failure of new projects and skepticism about future developments. Some users mention hair transplants and other potential alternatives like Alfatradiol and Fluridil, but acknowledge finasteride's dominance in the market due to its effectiveness and affordability.
community Father has decent amount of hair but im balding ?
A user is concerned about male pattern baldness despite their father having hair. Replies suggest visiting a dermatologist and considering finasteride or dutasteride, as natural methods are ineffective.
community Where does time go? Turning 30 soon and been on treatment for 8 years.
User started fin/min/niz at 23, switched to Dut at 24, and has been on treatments for 7 years. Despite occasional doubts, hair improved and user advises sticking with treatments.
community CRISPR treatment for AGA on the horizon after approval for blood disorders
CRISPR treatments for blood disorders have been approved, leading to discussions about its potential for treating hair loss (AGA). A study showed that editing a gene related to DHT sensitivity could lead to hair regrowth, suggesting CRISPR may eventually be used for AGA, but it's expected to be expensive and not soon available.