26 citations,
March 2012 in “Journal of Investigative Dermatology” New gene identification techniques have improved the understanding and classification of inherited hair disorders.
October 2023 in “Research Review” The document discusses cutaneous tumors of pilar origin, which develop from skin appendages like hair follicles and sebaceous glands. These tumors can be benign or malignant and may be associated with genetic syndromes. Benign neoplasms include Trichoblastoma, Pilomatricoma, Trichilemmoma, Trichofolliculoma, and Fibrofolliculoma, while malignant ones include Pilomatriceal carcinoma and proliferating trichilemmal tumors. Malignant tumors are rare but can be locally aggressive with potential for nodal involvement and distant metastasis. The tumors are categorized based on follicular differentiation, and several syndromes linked to these tumors involve gene abnormalities.
109 citations,
September 2011 in “Human molecular genetics online/Human molecular genetics” New treatments targeting specific genes show promise for treating keratin disorders.
24 citations,
October 2014 in “Cold Spring Harbor Perspectives in Medicine” Genetic research has advanced our understanding of skin diseases, but complex conditions require an integrative approach for deeper insight.
November 2019 in “Harper's Textbook of Pediatric Dermatology” Understanding normal hair growth and loss in children is key to diagnosing and treating hair disorders.