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Glossary Gas Chromatography-Mass Spectrometry

combines gas chromatography and mass spectrometry to identify substances

Gas Chromatography-Mass Spectrometry (GC-MS) is an analytical technique that combines the features of gas chromatography and mass spectrometry to identify different substances within a test sample. It is widely used in various fields, including forensic science, environmental analysis, and drug testing, to detect and quantify compounds with high precision and sensitivity.

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research Gas Chromatography Tandem Mass Spectrometry for Biomarkers of Alcohol Abuse in Human Hair

18 citations , March 2010 in “Therapeutic Drug Monitoring”

This study developed a faster method to analyze fatty acid ethyl esters in human hair, potentially distinguishing alcohol consumption levels more efficiently.

Phytochemical Analyses of Ziziphus Jujuba Mill. Var. Spinosa Seed by Ultrahigh Performance Liquid Chromatography-Tandem Mass Spectrometry and Gas Chromatography-Mass Spectrometry

research Phytochemical analyses of Ziziphus jujuba Mill. var. spinosa seed by ultrahigh performance liquid chromatography-tandem mass spectrometry and gas chromatography-mass spectrometry

38 citations , January 2013 in “Analyst”

This study identified the main secondary metabolites in Ziziphus jujuba seeds and confirmed that UPLC-MS/MS and GC-MS effectively demonstrate their pharmaceutical quality.

research Assessment of Circulating Sex Steroid Levels in Prepubertal and Pubertal Boys and Girls by a Novel Ultrasensitive Gas Chromatography-Tandem Mass Spectrometry Method

169 citations , November 2009 in “The Journal of Clinical Endocrinology & Metabolism”

This study found that prepubertal girls have significantly higher levels of estrogens and androgen metabolites compared to age-matched boys, which may contribute to their earlier onset of puberty.

research Sex steroid levels in corresponding cerebrospinal fluid and serum samples quantified by mass spectrometry in men

1 citations , November 2023 in “Endocrine Connections”

This study developed a validated gas chromatography–tandem mass spectrometry assay to assess sex steroid hormones in cerebrospinal fluid, finding substantial levels of DHEA, androstenedione, and testosterone, with strong correlations to serum levels, providing insight into sex steroid dynamics in the human CNS.

research Segmental Hair Analysis for 11-Nor- 9-Tetrahydrocannabinol-9-Carboxylic Acid and the Patterns of Cannabis Use

30 citations , March 2012 in “Journal of Analytical Toxicology”

This study found that concentrations of THCCOOH in hair do not correlate well with self-reported cannabis use due to inaccuracies in the self-reported data, but it provides preliminary insights into usage patterns.

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