research Inhibitory Amino Acid Transmitters Associated With Axons in Presynaptic Apposition to Cutaneous Primary Afferent Axons in the Cat Spinal Cord
Presynaptic inhibition of certain nerve fibers in cats is mainly controlled by GABA and glycine.
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research Synthesis and Actions of 5α-Reduced Metabolites of Testosterone in the Nervous System
Testosterone and its metabolites affect brain functions and could help treat neurological disorders.
research The Leaves of Crataeva Nurvala Buch-Ham. Modulate Locomotor and Anxiety Behaviors Possibly Through GABAergic System
Crataeva nurvala leaves may help reduce anxiety and improve sleep.
research GABAA Receptor Modulation by Neurosteroids in Models of Temporal Lobe Epilepsies
Neurosteroids change how GABA_A receptors work in the brain, which could be important for treating temporal lobe epilepsy.
research Novel Modulatory Effects of Neurosteroids and Benzodiazepines on Excitatory and Inhibitory Neurons Excitability: A Multi-Electrode Array Recording Study
Neurosteroids and benzodiazepines reduce neuron excitability, with lasting effects on inhibitory neurons.
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5 / 8 resultscommunity 5 alpha reductase type 1 is in brain tissue producing the main endogenous gabaergic allopregnanolone, not 2. How can finasteride as a 5ar2 lower that?
Finasteride and dutasteride are discussed for hair loss, with concerns about their effects on neurosteroids and potential side effects like depression. Alternatives like topical estrogen and lifestyle changes are considered, with varying opinions on mental health and hair regrowth.
community What to do if fin is still not working after 2.5 years
The user is experiencing increased hair loss despite using finasteride and oral minoxidil and is hesitant to switch to dutasteride due to side effects and family planning concerns. Alternatives suggested include dutasteride, microneedling, and addressing stress or nutrient deficiencies.
community risks with finasteride and dutasteride
Finasteride and dutasteride have potential risks, including post-finasteride syndrome, but are commonly used for hair loss. RU58841, minoxidil, and needling are suggested as alternatives, though all treatments carry risks.
community Huge anxiety after taking finasteride
The user experiences severe anxiety and physical symptoms after taking finasteride and is seeking alternative hair loss treatments since dutasteride is unavailable. They suspect an allergic reaction to finasteride and have stopped using it.
community Finasteride does deplete important nuero-active steroids
Finasteride can reduce neuroactive steroids, causing side effects like depression, anxiety, and sexual dysfunction. Some users experience persistent symptoms after stopping finasteride, while others use alternative treatments like topical solutions.