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research Clinicopathologic and Trichoscopic Features of Keratosis Follicularis Spinulosa Decalvans: A Case Series Study

December 2023 in “Journal of dermatology”

The study concluded that key signs of Keratosis follicularis spinulosa decalvans are changes in terminal hair and vellus hair follicles, which likely start the inflammation and damage to hair follicles.

research Heparan Sulfate Regulates Hair Follicle and Sebaceous Gland Morphogenesis and Homeostasis

42 citations , July 2014 in “Journal of biological chemistry/The Journal of biological chemistry”

Heparan sulfate is important for hair growth, preventing new hair formation in mature skin, and controlling oil gland development.

research Sphingolipid Metabolism Orchestrates the Establishment of the Adult Hair Follicle Stem Cell Niche to Control Skin Homeostasis

January 2024 in “bioRxiv (Cold Spring Harbor Laboratory)”

A specific enzyme is essential for proper hair follicle stem cell development and healthy skin.

Confocal Microscopy and Optical Coherence Tomography of Inflammatory Skin Diseases in Hairs and Pilosebaceous Units: A Systematic Review

research Confocal Microscopy and Optical Coherence Tomography of Inflammatory Skin Diseases in Hairs and Pilosebaceous Units: A Systematic Review

May 2023 in “Experimental Dermatology”

RCM and OCT are effective for diagnosing and monitoring hair-related skin diseases but lack standardized protocols and need more research.

research Clinical and Molecular Genetic Studies in Hereditary Hair Loss

August 2021

Researchers found a genetic link for hereditary hair loss but need more analysis to identify the exact gene.

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community No side effects on pyrilutamide / KX-826 so far

in Research/Science 206 upvotes 3 years ago

User TopBack56 and friends tried pyrilutamide (KX-826) for hair loss without experiencing negative side effects. They observed fine vellus hairs but no thick hair growth yet, and plan to add GT20029 to their regime after safety trials.

community PP405 Identity Research

in Research 292 upvotes 1 month ago

PP405 is a potential hair loss treatment that inhibits mitochondrial pyruvate carriers, increasing lactate dehydrogenase activity and stimulating hair follicle stem cells. In a phase 1 trial, 31% of participants showed over 20% hair density increase with PP405 treatment.

community Dht kills hair, but no one says why?

in Finasteride/Dutasteride 40 upvotes 1 month ago

DHT affects hair follicles, contributing to hair loss, but the exact mechanism is unclear. Treatments like finasteride and minoxidil are used to manage hair loss, though they may have side effects and varying effectiveness.

community Dental technician is convinced that he has found the cause of pattern hair loss

in Research/Science 310 upvotes 1 year ago

A dental technician claims malocclusion causes pattern hair loss due to poor scalp circulation. Users debate this, noting treatments like finasteride, minoxidil, and microneedling focus on DHT and blood flow.

community The Real Cause Of Androgenetic Alopecia

in Research/Science 680 upvotes 11 months ago

Androgenetic alopecia is caused by DHT affecting hair growth. Finasteride and minoxidil are used to manage hair loss by blocking DHT and promoting hair growth.

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