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research Functional analysis of the stratum corneum of scalp skin: studies in patients with alopecia areata and androgenetic alopecia

52 citations , December 2000 in “Archives of Dermatological Research”

This study found that the stratum corneum of scalp skin in humans has distinct functional characteristics compared to the facial skin and volar forearm, including higher hydration levels and intermediate epidermal turnover rates.

research Functional analysis of keratin components in the mouse hair follicle inner root sheath

23 citations , February 2004 in “British Journal of Dermatology”

Keratin in mouse hair follicles is complex and plays specific roles.

research Functional analyses of a novel missense and other mutations of the vitamin D receptor in association with alopecia

20 citations , July 2017 in “Scientific Reports”

This study found that a novel missense mutation in the vitamin D receptor caused hereditary 1,25-dihydroxyvitamin D-resistant rickets with alopecia by disrupting protein function, highlighting the importance of DNA binding in hair development.

research Functional Analysis of VDR Gene Mutation R343H in A Child with Vitamin D-Resistant Rickets with Alopecia

6 citations , November 2017 in “Scientific reports”

This study found that a novel R343H mutation in the vitamin D receptor gene impairs its transcription activity, contributing to hereditary vitamin D-resistant rickets and alopecia in the affected family.

Functional Analysis of Vitamin D Receptor Using Adenovirus Vector

research Functional analysis of vitamin D receptor (VDR) using adenovirus vector

4 citations , February 2023 in “Journal of steroid biochemistry and molecular biology/The Journal of steroid biochemistry and molecular biology”

In this study, only Vdr-knockout rats showed both abnormal skin formation and alopecia, which may provide insights into vitamin D receptor function and its role in the hair growth cycle.

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Community Join

5 / 865 results

community A meta analysis of 18 popular hair loss treatments. An 2022 guide on efficacy. From finasteride and minoxidil to caffeine shampoo, saw palmetto and biotin. 96 Scientific References included.

103 upvotes 4 years ago

Most hair loss treatments are ineffective; only finasteride, dutasteride, and minoxidil show effectiveness.

community Finasteride - impact on Neurosteroids, which yes, \are important and not a garbage hormone

in Research/Science 163 upvotes 1 year ago

Finasteride may affect neurosteroids, impacting mood and sexual function, with varied user experiences. Some report side effects like depression and sexual dysfunction, while others find it effective for hair retention or prefer alternatives like Dutasteride or topical treatments.

community DHT and 5AR respect post, it's importance within the brain

in Research/Science 111 upvotes 2 years ago

The conversation discusses whether to use finasteride for hair loss, considering its role in inhibiting DHT and 5AR, which can affect brain function and mood. Some users report anxiety and depression from finasteride, while others do not experience these side effects and emphasize the importance of DHT for brain and prostate health.

community Fin and Brain Fog

7 upvotes 10 years ago

The conversation discusses concerns about brain fog potentially caused by finasteride use, with some users sharing personal experiences of cognitive issues and others suggesting it might be paranoia or unrelated. The original poster decides to stop using finasteride to see if their cognitive function improves.

community Attention Finasteride / Dutasteride and Your liver

374 upvotes 1 year ago

Finasteride may cause elevated liver enzymes, potentially leading to liver issues, though this is rare. Users should monitor liver function and consider topical alternatives if liver sensitivity occurs.

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Learn

8 / 801 results

learn Thymosin Beta 4

What is Thymosin Beta 4, and why is it being researched in relation to hair follicle function and regeneration? Thymosin Beta 4 is a peptide being researched for its potential to enhance hair follicle regeneration.

learn Stem Cell Factor

learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

learn Beta Polypeptide

learn Neem Oil

natural substance from Neem tree with medicinal and pesticidal properties

learn Glycerin

Does topical glycerin have any effect on hair thickness or follicle function? Topical glycerin primarily hydrates hair but does not increase thickness or follicle function.

learn Selenium

What is Selenium and why is it important for healthy hair and scalp function? Selenium is essential for hair health due to its antioxidant properties and role in thyroid function.

learn zinc PCA

Why is zinc important for preventing hair loss and supporting hair follicle function? Zinc is crucial for hair follicle health, supporting growth and repair processes.

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Clinics

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