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research 1394 Long non-coding RNA AL136131.3 inhibits hair growth through mediating glycolysis in androgenetic alopecia

April 2023 in “Journal of Investigative Dermatology”

This study found that overexpression of the lncRNA AL136131.3 may inhibit hair shaft growth and promote hair follicle apoptosis in androgenetic alopecia by influencing key metabolic pathways.

research Role of Stearoyl-CoA Desaturase-1 in Skin Integrity and Whole Body Energy Balance

67 citations , December 2013 in “Journal of Biological Chemistry”

This review discusses the role of the enzyme Δ9-desaturase-1 in skin lipid regulation and whole-body energy balance in mice and reports no new experimental results.

research Causal Relationship Between Blood Metabolomics and Female Pattern Hair Loss: A Bidirectional Mendelian Randomization Study

February 2025 in “Clinical Cosmetic and Investigational Dermatology”

This study used Mendelian randomization to explore associations between 1400 blood metabolites and female-pattern hair loss, finding 23 metabolites and 4 metabolic ratios linked to the condition, while identifying fructose/mannose metabolism as a significant pathway.

The Effects of the Ethanol Extract of Allium Ascalonicum L. in High-Fat High-Fructose Induced Insulin Resistance in Swiss-Webster Male Mice

research The Effects of the Ethanol Extract of Allium Ascalonicum L. in High-Fat-High-Fructose-Induced Insulin Resistance Swiss-Webster Male Mice

May 2025 in “Journal of Experimental Pharmacology”

This study found that Allium ascalonicum L. extract may improve insulin resistance by increasing insulin tolerance test values and lowering blood glucose levels, though more research is needed to understand its effects on metabolic disorders.

research Metabolic and Vascular Inflammation in Alopecia Areata: Linking Uric Acid, Lipid Imbalance and ICAM ‐1 Upregulation

December 2025 in “Experimental Dermatology”

This study found that uric acid-linked microvascular dysfunction may play a role in alopecia areata, suggesting that targeting endothelial function and uric acid regulation could be a potential management strategy.

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community 57% increased chance of pattern hair loss independently associated with the consumption of sugary beverages in men (p<0.001).

297 upvotes 2 years ago

Sugary beverages increase the risk of pattern hair loss in men by 57%, and type 2 diabetes is linked to female pattern hair loss. Reducing sugar intake and using treatments like finasteride and minoxidil may help manage hair loss.

community Ray Peat: Testosterone Isn’t the Culprit, Prolactin and Cortisol Drive Hair Loss (2016)

in Research/Science 110 upvotes 10 months ago

Prolactin and cortisol are identified as key factors in hair loss, with stress hormones impacting hair shedding. Finasteride and minoxidil are effective treatments, while DHT's role and individual sensitivity are significant factors.

community The Association between Sugar-Sweetened Beverages and Male Pattern Hair Loss in Young Men

136 upvotes 1 year ago

Excessive sugar consumption may contribute to male pattern hair loss by increasing androgen sensitivity and insulin resistance, but genetics play a significant role. Treatments like minoxidil and finasteride are suggested for managing hair loss, while reducing sugar intake and maintaining a healthy lifestyle may help mitigate its progression.

community Yes your lifestyle and diet has its role in hair loss.

in Chat 296 upvotes 1 year ago

Diet and lifestyle changes can reduce hair shedding but won't regrow hair lost to genetic male pattern baldness. Treatments like finasteride and dutasteride are necessary for significant hair regrowth.

community Finasteride and Eye Problems: You’re Not Going Crazy

in Finasteride/Dutasteride 503 upvotes 1 year ago

Finasteride can cause dry eyes and vision issues due to its impact on the meibomian glands. Users have mixed experiences, with some experiencing eye discomfort and others having no side effects.

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