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research Dynamic Changes in Fibroblast Subpopulations Drive Development of Radiation-Induced Skin Fibrosis Through the Fra/c-Jun Pathway

April 2023 in “Journal of Investigative Dermatology”

Radiation treatment causes skin fibrosis by increasing certain fibroblast subpopulations, but using a c-Jun inhibitor or fat grafting can reduce this effect.

research Activator Protein-1 Activity Regulates Epithelial Tumor Cell Identity

March 2023

Inhibiting AP-1 changes skin tumor types and affects tumor cell identity.

research Activator Protein-1 Activity Regulates Epithelial Tumor Cell Identity

March 2023

Inhibiting AP-1 changes skin tumor types and affects tumor cell identity.

research Regulation of Involucrin Gene Expression

138 citations , June 2004 in “Journal of Investigative Dermatology”

Involucrin gene expression is controlled by specific proteins and signaling pathways.

research Two Mechanisms Regulate Keratin K15 Expression in Keratinocytes: Role of PKC/AP-1 and FOXM1 Mediated Signaling

35 citations , June 2012 in “PloS one”

Keratin 15 expression in skin cells is regulated by two mechanisms involving PKC/AP-1 and FOXM1.

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community How significant is the difference between 0.5mg Dut and 1mg Fin?

in Finasteride/Dutasteride 11 upvotes 1 year ago

0.5mg dutasteride reduces scalp DHT more than 1mg finasteride, leading to better hair regrowth results. Users report significant improvement with dutasteride compared to finasteride.

community I promise it works. Topical minox + finasteride

in Update 1723 upvotes 7 months ago

Topical minoxidil and oral finasteride can effectively improve hair growth and slow hair loss, though results may vary. Consistency is important for achieving significant improvement.