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Glossary Follicular Infundibulum

upper part of hair follicle where sebum exits

The follicular infundibulum is the upper part of a hair follicle, extending from the skin's surface down to the point where the sebaceous (oil) gland opens into the follicle. This region is crucial for the passage of sebum and dead skin cells to the skin's surface, and its blockage can lead to conditions like acne.

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Research

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research Activity of type 1 5α-reductase is greater in the follicular infrainfundibulum compared with the epidermis

12 citations , February 1997 in “British Journal of Dermatology”

This study found that 5α–reductase activity is higher in infrainfundibular keratinocytes compared to interfollicular epidermal keratinocytes, suggesting a potential role in acne-related follicular changes.

Expression of the L-Fucose Moiety on Infrainfundibular Follicular Keratinocytes of Terminal Follicles, Its Decreased Expression on Vellus and Indeterminate Follicles of Androgenetic Alopecia, and Re-Expression in Drug-Induced Hair Regrowth

research Expression of the L-Fucose Moiety on Infrainfundibular Follicular Keratinocytes of Terminal Follicles, Its Decreased Expression on Vellus and Indeterminate Follicles of Androgenetic Alopecia, and Re-Expression in Drug-Induced Hair Regrowth

9 citations , January 1992 in “Journal of Investigative Dermatology”

This study found distinct differences in UEA I glycoprotein binding on follicular keratinocytes between anagen and telogen hair follicles, with staining associated with follicle length and regrowth.

research Follicular Hybrid Cyst With Isthmic-Catagen, Pilomatrical, and Syringocystadenoma Papilliferum Components

2 citations , June 2012 in “American Journal of Dermatopathology”

This case study describes a rare cutaneous follicular hybrid cyst intimately associated with syringocystadenoma papilliferum, proposing a potential relationship with the infrainfundibulum based on keratin expression.

research Epithelial keratin and filaggrin expression in seborrheic keratosis: evaluation based on histopathological classification

12 citations , June 2013 in “International Journal of Dermatology”

This study found that different types of seborrheic keratosis demonstrate diverse differentiation patterns, highlighting its undifferentiated and hyperproliferative state with varying keratinization directions.

research Generalized trichoepitheliomas with alopecia and myasthenia gravis: Clinicopathologic and immunohistochemical study and comparison with classic and desmoplastic trichoepithelioma

54 citations , November 1986 in “Journal of the American Academy of Dermatology”

This case report identifies a potential new syndrome characterized by trichoepitheliomas and alopecia, which may be associated with myasthenia gravis.

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Learn

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learn Hair Transplant

What is Follicular Unit Extraction (FUE) in hair transplants? Follicular Unit Extraction (FUE) is a minimally invasive hair transplant method that extracts individual hair follicles.
What is Follicular Unit Transplantation (FUT) in hair transplants? Follicular Unit Transplantation (FUT) involves removing a scalp strip for hair restoration.

learn Follicusan

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community Information regarding Follicusan DP?

3 upvotes 2 years ago

Follicusan DP is discussed as a potential alternative to Minoxidil without side effects, but information is scarce. It is noted to be of German origin and details on its mechanism are limited.

community Targeted Follicular Finasteride Delivery: A Low-Systemic Strategy

15 upvotes 5 months ago

A peptide-based delivery system for finasteride shows promise in reducing systemic side effects while maintaining hair growth effectiveness. Combining this with other treatments like minoxidil and RU58841 could enhance results with lower systemic absorption.

community What is the deal with "longitudinal partial follicular unit transplantation"

5 upvotes 6 years ago

Longitudinal partial follicular unit transplantation involves extracting part of the donor follicular unit, allowing the donor area to be overharvested without noticeable hair loss. The conversation questions if this method is practiced in clinics or if it's theoretical, and whether it relates to hair cloning or multiplication.

community What is the deal with "longitudinal partial follicular unit transplantation"

3 upvotes 6 years ago

Longitudinal partial follicular unit transplantation involves extracting part of the donor follicular unit, allowing the donor area to maintain hair production and potentially increasing transplant yield. The conversation questions if this method is practiced in clinics or remains theoretical, and whether it relates to hair cloning or multiplication.

community Can single hairs follicules be able to produce two hairs once again with treatment? Never saw a study about that.

in Finasteride/Dutasteride 11 upvotes 2 years ago

The conversation is about whether treatments like finasteride, dutasteride, and minoxidil can make single hair follicles produce multiple hairs again. The user is curious if these medications can thicken hair and prolong the growth phase.

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Clinics

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Hair Transplant
Australian Hair & Scalp Clinics-Hair Regrowth by Herbal Follicular ActivationMelbourne, VIC · AU

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