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      learn Tretinoin

      the gold standard retinoid in dermatology that's also helpful for hair regrowth alongside Minoxidil

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      natural substance from Neem tree with medicinal and pesticidal properties

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      a nonsteroidal anti-androgen, most commonly used orally for women

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      glaucoma medication with hair follicle stimulant effects

      learn PP405

      mitochondrial pyruvate carrier (MPC) inhibitor by Pelage in early trials

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      community How is scalp sensitivity even measured?

      in Research/Science  9 upvotes 2 weeks ago
      There are no tests to determine genetic follicle sensitivity for hair loss, and conclusions are based on hypothetical or post-balding observations. Finasteride is mentioned as an easy, consistent treatment option compared to natural treatments.

      community Why is it that low testosterone causes hair loss as well? How can I be balding?

      in Chat  158 upvotes 1 year ago
      The conversation discusses the confusion over low testosterone potentially causing hair loss, with users sharing personal experiences and knowledge about hair loss treatments like Finasteride. Some users suggest that hair follicle sensitivity to DHT, not testosterone levels, is the key factor in balding, and others discuss the side effects of hair loss medications.

      community why are beard gains on min usually permanent?

      in Minoxidil  43 upvotes 4 months ago
      Beard gains from minoxidil are usually permanent due to facial hair follicles' lower sensitivity to DHT. Scalp hair requires ongoing DHT suppression with treatments like finasteride, dutasteride, and RU58841 to maintain gains after stopping minoxidil.

      community Why does finasteride stop working?

      in Finasteride/Dutasteride  26 upvotes 1 year ago
      Finasteride may seem less effective over time due to increased DHT sensitivity or aging, but it still suppresses DHT. Switching to dutasteride offers stronger DHT suppression but may increase estrogen levels.