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research A Practical Guide to Hair Graft Placement Using the Sharp Implanter Method

July 2023 in “Clinical, Cosmetic and Investigational Dermatology”

This study explains surgical techniques for hair transplantation using the sharp implanter method, emphasizing 11 key principles that optimize efficiency and precision, and reports high graft survival and natural hair density when these principles are followed.

research Prachhan Karma with Lepa and Shirodhara – An Effective Treatment of Indralupta – A Case Study

June 2022 in “Asian Pacific journal of health sciences”

This study reports a case of Indralupta (Alopecia Areata) successfully treated using Ayurvedic methods including Prachhan karma, Lepa, and Shirodhara, offering an alternative to conventional treatments like minoxidil and steroids, which may have adverse effects.

research The transcriptional repressor CDP (Cutl1) is essential for epithelial cell differentiation of the lung and the hair follicle

165 citations , September 2001 in “Genes & development”

This study found that Cutl1 mutant mice experienced retarded lung differentiation and abnormal hair follicle morphogenesis, indicating the vital role of CDP in lung development and hair follicle cell-lineage specification.

research The Metabolism and Control Mechanism of Human Hair Follicles

22 citations , April 2015 in “Current problems in dermatology”

Human hair follicles have a unique metabolism that changes between growth stages and may contribute to baldness.

research Defolliculated (Dfl): A Dominant Mouse Mutation Leading to Poor Sebaceous Gland Differentiation and Total Elimination of Pelage Follicles

53 citations , July 2002 in “Journal of Investigative Dermatology”

The Dfl mutation in mice causes poor sebaceous gland function and complete hair loss.

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Community Join

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community Losing Hair from Microneedling?

4 upvotes 2 weeks ago

Microneedling can cause hair shedding due to follicle puncturing, especially when using a 1mm depth. Users suggest using a dermastamp with a depth of 0.6-1mm and caution against home microneedling to avoid damaging hair follicles.

community Best Microneedle Lengths To Stimulate Stem Cells

18 upvotes 2 years ago

Microneedling with needle lengths of 1.5mm to 2.5mm to stimulate hair follicle stem cells for potential hair growth. Using needles longer than 2.5mm is not recommended due to risk of puncturing veins in the scalp. A dermastamp is suggested over a roller.

community Pelage PP405: New Hair Growth from Inactive Follicular Units - Phase 2a results at AAD 2026

1080 upvotes 6 months ago

PP405, a topical treatment, shows promise for hair growth by activating inactive follicles, with 66% of participants experiencing positive results. The treatment is well-tolerated and may proceed directly to Phase 3 trials, offering a potential alternative to minoxidil and finasteride.

community Are Derma Rollers Actually Harmful in the Long Run?

in Microneedling 40 upvotes 1 year ago

Derma rollers may cause scarring alopecia, leading some to prefer dermastamps or dermapens for microneedling. Combining minoxidil with microneedling is effective, but proper technique and healing time are essential to prevent damage.

community questions regarding topical finasteride

in Finasteride 4 upvotes 7 years ago

The conversation discusses the potential effectiveness and risks of using topical finasteride for hair loss, with considerations about using DMSO as a vehicle for application. Concerns are raised about DMSO's safety, absorption issues, and the systemic effects of topical finasteride.

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Learn

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learn Microneedling

Technique that makes tiny punctures in the scalp with fine needles

learn Niacinamide

Does niacinamide support hair follicle nutrition? Niacinamide is a precursor of NAD+, a molecule cells use for energy. Whether it affects hair follicles in people has not been tested.

learn Scalp Micropigmentation

Will scalp micropigmentation damage my existing hair or follicles? Providers say SMP sits above the hair follicles and does not harm them. No study has tested this, and infection or scarring from any tattoo can affect the skin.

learn Redensyl

Does Redensyl regenerate follicles or only strengthen existing hair? No independent study has shown that Redensyl regenerates follicles or strengthens hair; the only human data are a small, unpublished manufacturer study.

learn Sulforaphane

Can sulforaphane protect hair follicles from inflammation and damage? In lab and mouse studies, sulforaphane reduced markers of inflammation and oxidative stress. No human study has tested whether it protects hair follicles.

learn Fluridil

Can daily Fluridil application stop hair follicle miniaturization? The single published fluridil trial (43 men; placebo-controlled for 3 months, then all on fluridil to 9 months) reported more hairs in the growth phase, but it never measured follicle diameter and has not been replicated — so whether daily use stops miniaturization is unproven, and community users describe stabilization rather than regrowth.

learn Follicusan

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