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research Confocal Laser Scanning Microscopy: An Excellent Tool for Tracking Compounds in the Skin

5 citations , November 2005

This review discusses the applications of confocal laser scanning microscopy in visualizing fluorescent compounds within the skin, noting its potential for tracking drug carriers and enhancing penetration studies, but reports no new results.

research Analysis of hair follicle penetration of lidocaine and fluorescein isothiocyanate-dextran 4 kDa using hair follicle-plugging method

19 citations , April 2013 in “Drug Development and Industrial Pharmacy”

This study highlights the significance of the hf pathway for the skin permeation of ionized and hydrophilic high molecular compounds, and the usefulness of hf-plugging in evaluating their skin permeability.

research Nanoparticle-Based Targeting of Vaccine Compounds to Skin Antigen-Presenting Cells By Hair Follicles and their Transport in Mice

119 citations , December 2008 in “The journal of investigative dermatology/Journal of investigative dermatology”

In this study, transcutaneously applied nanoparticles and viral vectors were shown to penetrate murine hair follicles, internalize in antigen-presenting cells, and induce immune responses, suggesting a promising approach for vaccine delivery.

research Pharmacological Effects of Natural Compounds Extracted from Urtica dioica Evaluated by in Silico and Experimental Methods

3 citations , October 2018 in “Revista de Chimie”

This review discusses the potential medicinal properties and pharmacokinetic features of nettle compounds ursolic acid and quercetin, highlighting quercetin as a promising candidate for antioxidant and anti-aging effects, but reports no new clinical results.

research A Fluorescence-based Lymphocyte Assay Suitable for High-throughput Screening of Small Molecules

9 citations , March 2017 in “Journal of Visualized Experiments”

This study introduced a novel in vitro murine assay using transgenic mice to identify immunomodulatory compounds, which identified 160 potential hits from 4,398 compounds screened.

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community Does DHT give you a leaner face?

in Finasteride/Dutasteride 44 upvotes 1 year ago

Finasteride and dutasteride may increase estrogen levels, leading to water retention and a fuller face. Users discuss managing these effects with lifestyle changes and supplements like zinc and DIM.

community Hair regrowth without drugs (99% natural) 25M

528 upvotes 3 months ago

A user shared their experience with hair regrowth using supplements like NAC and DIM, and briefly using minoxidil with microneedling. They reported some improvement in hair density, but the community questioned the effectiveness compared to traditional treatments like finasteride.

community Peptides that Stop Hair Loss? | In-depth Literature Review Video

76 upvotes 2 years ago

Peptides like TB500, KPV, GHK-CU, and BPC-157 are overhyped for hair growth with limited proven effectiveness in humans. Combining peptides with delivery methods like iontophoresis and sonophoresis shows promise, but many claims remain unproven.

community Does your hair also look depressingly awful under fluorescent lights?

in Chat 39 upvotes 1 year ago

Fluorescent lighting makes hair look thinner, causing concern about appearance. Some users consider treatments like DUT, while others share experiences of hair looking better in different lighting or conditions.

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